渕上 竜也 (フチガミ タツヤ)

Fuchigami Tatsuya

写真a

職名

講師

科研費研究者番号

10381211

現在の所属組織 【 表示 / 非表示

  • 専任   琉球大学   病院   講師  

取得学位 【 表示 / 非表示

  • 琉球大学 -  医学博士  その他 / その他

研究キーワード 【 表示 / 非表示

  • 臨床麻酔科学,集中治療医学,心臓血管麻酔科学,虚血性脊髄障害,痙性対麻痺

主たる研究テーマ 【 表示 / 非表示

  • 人工呼吸

  • 痙性対麻痺

  • 虚血性脊髄障害

  • くも膜下オピオイド投与が脊髄神経に及ぼす効果におけるATP感受性カリウムチャンネルの関与に関する研究

  • モルヒネくも膜下投与による虚血性脊髄傷害の増悪作用のメカニズムに関する研究

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論文 【 表示 / 非表示

  • オミクロン株流行前後のCOVID-19入院患者におけるリハビリテーション介入と経過の特徴

    宮森 匠, 梅村 武寛, 大城 徹也, 垣花 学, 徳重 明央, 渕上 竜也, 星野 宗勳, 嶺井 陽, 宮城 一也, 山本 和子

    日本呼吸ケア・リハビリテーション学会誌 ( 一般社団法人 日本呼吸ケア・リハビリテーション学会 )  34 ( 3 ) 246 - 252   2025年08月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    <p>目的:COVID-19入院患者のリハビリテーションに関して,オミクロン変異株の流行前後の特徴を明らかにする目的で行った単施設後方視的観察研究である.</p><p>方法:2020年4月から2023年1月の間に琉球大学病院に入院したCOVID-19患者を2022年1月1日の前(A群)と以後(B群)に分類し,患者背景,臨床情報,リハビリテーション内容と経過を比較した.</p><p>結果:A群81名(平均68歳),B群114名(平均72歳)であった.基礎疾患でB群に心(22%)・腎疾患(18%)が多く,A群ではCOVID-19重症者が多かった(56%).介入したリハビリテーションはA群で腹臥位(56%)・離床(57%),B群で自主練習(60%)が主体であった.A群でPerformance Status(PS)回復と歩行自立までの期間が長かったが(20日,15日),退院時PSの回復率は大きかった.</p><p>結論:COVID-19患者のリハビリテーションは各流行期の臨床的特徴を認識し,身体機能の回復と廃用症候群の予防を使い分けた計画の立案が必要である.</p>

  • Post COVID-19 condition in hospitalized survivors after one year of infection during the Alpha- and Delta-variant dominant waves in Japan: COVID-19 Recovery Study II

    Muto, Y; Hosozawa, M; Hori, M; Iba, A; Maruyama, S; Morioka, S; Teruya, K; Nishida, T; Harada, T; Miike, S; Kawauchi, A; Kato, H; Hatakeyama, J; Asahi, T; Nakamura, K; Sato, Y; Oshima, T; Nagashima, F; Ota, K; Fujitani, S; Fuchigami, T; Yoshida, H; Nosaka, N; Hattori, T; Taniguchi, H; Kamij, H; Iso, H

    JOURNAL OF EPIDEMIOLOGY ( 日本疫学会 )  35 ( 7 ) 330 - 340   2025年07月

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    <p><b>Background:</b> Evidence of post-COVID-19 condition (PCC) in the Alpha- and Delta-variant dominant waves is limited.</p><p><b>Methods:</b> In a nationwide multicenter cohort study in collaboration with 20 hospitals, we collected data using self-administered questionnaires and electronic medical records of participants aged 20 or more diagnosed with COVID-19, hospitalized between April 1, 2021 and September 30, 2021, and discharged alive. Descriptive statistics were analyzed for PCC and mental health (HADS anxiety and depression scores), comparing Alpha- and Delta-variant dominant waves.</p><p><b>Results:</b> We analyzed 1,040 patients (median age, 57 [IQR 49–66] years; men, 66.2%). Of the respondents, 45.4% had at least one PCC symptom 1 year after infection. The common symptoms included dyspnea (20.7%), fatigue/malaise (17.6%), muscle weakness (15.4%), decrease in concentration (13.4%), and sleep disorder (13.3%), followed by brain fog (8.4%). Among patients with PCC, 14.0% had anxiety (HADS-Anxiety ≥11), and 18.6% had depression (HADS-Depression ≥11), with four times higher proportions than those without PCC; only small variations by age, sex, and waves were observed. Associated factors for PCC were age 40 years or over, women, severity of COVID-19 during hospitalization, ex-smokers who quit smoking before COVID-19 infection and being infected during the Delta-variant dominant wave.</p><p><b>Conclusion:</b> The study described the prevalence of PCC, associated factors, and mental health of COVID-19 survivors hospitalized during the Alpha- and Delta-variant dominant waves in Japan. Further follow-up will be conducted to examine the longer-term impact of COVID-19 on PCC, complications, daily life, and socioeconomic status.</p>

  • Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disease-19.

    Hatakeyama J, Nakamura K, Inoue S, Liu K, Yamakawa K, Nishida T, Ohshimo S, Hashimoto S, Kanda N, Aso S, Suganuma S, Maruyama S, Ogata Y, Takasu A, Kawakami D, Shimizu H, Hayakawa K, Yoshida T, Oshima T, Fuchigami T, Yawata H, Oe K, Kawauchi A, Yamagata H, Harada M, Sato Y, Nakamura T, Sugiki K, Hakozaki T, Beppu S, Anraku M, Kato N, Iwashita T, Kamijo H, Kitagawa Y, Nagashima M, Nishimaki H, Tokuda K, Nishida O

    Journal of intensive care ( Journal of Intensive Care )  13 ( 1 ) 7   2025年02月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

  • Early Rehabilitation Interventions by Physical Therapists for Severe COVID-19 Patients Were Associated With Decreased Incidence of Post-ICU Physical Impairment.

    Oku S, Hatakeyama J, Liu K, Tojo K, Idei M, Inoue S, Yamakawa K, Nishida T, Ohshimo S, Hashimoto S, Maruyama S, Ogata Y, Kawakami D, Shimizu H, Hayakawa K, Fujino Y, Oshima T, Fuchigami T, Yawata H, Oe K, Kawauchi A, Yamagata H, Harada M, Sato Y, Nakamura T, Sugiki K, Hakozaki T, Beppu S, Anraku M, Kato N, Iwashita T, Kamijo H, Kitagawa Y, Nagashima M, Nishimaki H, Tokuda K, Nishida O, Nakamura K

    Annals of rehabilitation medicine ( Annals of Rehabilitation Medicine )  49 ( 1 ) 49 - 59   2025年02月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

  • Relationship between critical care nutrition and post-intensive care syndrome in surviving ventilated patients with COVID-19: a multicenter prospective observational study

    Nakamura, K; Hatakeyama, J; Liu, KB; Yamakawa, K; Nishida, T; Ohshimo, S; Inoue, S; Hashimoto, S; Maruyama, S; Kawakami, D; Ogata, Y; Hayakawa, K; Shimizu, H; Oshima, T; Fuchigami, T; Nishida, O

    JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION ( 一般社団法人 日本酸化ストレス学会 )  74 ( 1 ) 74 - 81   2024年01月

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    <p>The impact of nutrition therapy in the acute phase on post-intensive care syndrome (PICS) remains unclear. We conducted a multicenter prospective study on adult patients with COVID-19 who required mechanical ventilation for more than three days. The questionnaire was mailed after discharge. Physical PICS, defined as less than 90 points on the Barthel index (BI), was assigned as the primary outcome. We examined the types of nutrition therapy in the first week that affected PICS components. 269 eligible patients were evaluated 10 months after discharge. Supplemental parenteral nutrition (SPN) >400 ‍kcal/day correlated with a lower occurrence of physical PICS (10% vs 21.92%, <i>p</i> = 0.042), whereas the amounts of energy and protein provided, early enteral nutrition, and a gradual increase in nutrition delivery did not, and none correlated with cognitive or mental PICS. A multivariable regression analysis revealed that SPN had an independent impact on physical PICS (odds ratio 0.33, 95% CI 0.12–0.92, <i>p</i> = 0.034), even after adjustments for age, sex, body mass index and severity. Protein provision ≥1.2 ‍g/kg/day was associated with a lower occurrence of physical PICS (odds ratio 0.42, 95% CI 0.16–1.08, <i>p</i> = 0.071). In conclusion, SPN in the acute phase had a positive impact on physical PICS for ventilated patients with COVID-19.</p>

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科研費獲得情報 【 表示 / 非表示

  • 遅発性脊髄障害とDセリン~ノックアウトマウスを用いた研究~

    基盤研究(C)

    課題番号: 25462406

    研究期間: 2013年04月  -  2016年03月 

    代表者: 渕上 竜也  研究分担者: 垣花 学 琉球大学, 大学院医学研究科, 教授 (20274897) 大城 匡勝 琉球大学, 医学部附属病院, 助教 (00315483) 中村 清哉 琉球大学, 大学院医学研究科, 准教授 (00363680)

    直接経費: 3,800,000(円)  間接経費: 1,140,000(円)  金額合計: 4,940,000(円)

  • 脊髄虚血後の痙性対麻痺に及ぼすα2アドレナリン受容体アゴニストの鎮痙作用

    基盤研究(C)

    課題番号: 22591742

    研究期間: 2010年04月  -  2012年03月 

    代表者: 渕上 竜也  研究分担者: 垣花 学 琉球大学, 大学院・医学研究科, 准教授 (20274897) 照屋 孝二 琉球大学, 医学部, 助教 (50437985)

    直接経費: 3,300,000(円)  間接経費: 990,000(円)  金額合計: 4,290,000(円)