Shiroma Ayano

写真a

Researcher Number(JSPS Kakenhi)

50751567
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Current Affiliation Organization 【 display / non-display 】

  • Duty   University of the Ryukyus   Graduate School of Medicine  

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External Career 【 display / non-display 】

  • 2014.04
    　
    　

    University of the Ryukyus, Graduate School of Medicine, Instructor  

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Published Papers 【 display / non-display 】

  • Cerebellar Contribution to Pattern Separation of Human Hippocampal Memory Circuits.

    Shiroma A, Nishimura M, Nagamine H, Miyagi T, Hokama Y, Watanabe T, Murayama S, Tsutsui M, Tominaga D, Ishiuchi S

    Cerebellum (London, England) ( Cerebellum )  15 ( 6 ) 645 - 662   2016.12 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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  • Cerebellar contribution to pattern separation of human hippocampal memory circuits

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    博士論文（医） ( University of the Ryukyus )    1 - 18   2016.04

    Type of publication: Research paper (other science council materials etc.)

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    The cerebellum is a crucial structure for cognitive function as well as motor control. Benign brain tumors such as schwannomas, meningiomas, and epidermoids tend to occur in the cerebellopontine angle cisterns and may cause compression of the posterior lateral cerebellum near the superior posterior fissure, where the eloquent area for cognitive function was recently identified. The present study examined cognitive impairment in patients with benign cerebellar tumors before and after surgical intervention in order to clarify the functional implications of this region in humans. Patients with cerebellar tumors showed deficits in psychomotor speed and working memory compared with healthy controls. Moreover, these impairments were more pronounced in patients with right cerebellar tumors. Functional magnetic resonance imaging during performance of a lure task also demonstrated that cerebellar tumors affected pattern separation or the ability to distinguish similar experiences of episodic memory or events with discrete, non-overlapping representations, which is one of the important cognitive functions related to the hippocampus. The present findings indicate that compression of the human posterior lateral cerebellum affects hippocampal memory function. （管理者追加）リポジトリ登録情報を移行しました。確認のうえ、加除修正をしてください。

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