Current Affiliation Organization 【 display / non-display 】

Current Affiliation Organization 【 display / non-display 】

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External Career 【 display / non-display 】

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Research Areas 【 display / non-display 】

Published Papers 【 display / non-display 】

Published Papers 【 display / non-display 】

• A Case of Myxoid Solitary Fibrous Tumor With Villiform Histology in Pterygopalatine Fossa.

  Kobashigawa S, Nakayoshi H, Maeda H, Iraha Y, Nishie A, Kawakami F

  Pathology international ( Pathology International )  76 ( 5 ) e70123   2026.05 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• Key Points Regarding Recent Trend of Tracheo-esophageal Foreign Bodies

  Maeda H.

  Nihon Kikan Shokudoka Gakkai Kaiho ( The Japan Broncho-esophagological Society )  77 ( 2 ) 178 - 180   2026.04

  Type of publication: Research paper (scientific journal)

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    CiNii Research

• Nutritional and Inflammatory Markers Associated with Complete Response to Near-Infrared Photoimmunotherapy in Recurrent Head and Neck Squamous Cell Carcinoma.

  Hirakawa H, Ikegami T, Kinjyo H, Agena S, Nakayoshi H, Miyahira T, Kondo S, Kise N, Kayo Y, Maeda H, Suzuki M

  Cancers ( Cancers )  18 ( 6 )   2026.03 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

  　View Summary

  Background/Objectives: Near-infrared photoimmunotherapy (NIR-PIT) provides tumor-selective cytotoxicity with minimal collateral tissue damage and has emerged as a novel treatment option for recurrent head and neck squamous cell carcinoma (HNSCC). However, biomarkers that predict treatment response to NIR-PIT remain poorly defined. Therefore, this study aimed to exploratorily determine whether baseline nutritional and inflammatory composite biomarkers are associated with complete response to NIR-PIT in patients with recurrent HNSCC. Methods: Fifteen non-surgical candidates with recurrent HNSCC underwent NIR-PIT between January 2022 and December 2025. Baseline composite nutritional indices and inflammatory markers, including the systemic inflammation response index (SIRI), were assessed before and 4-8 weeks post-treatment. Tumor response was evaluated according to RECIST version 1.1. Exploratory comparisons between complete response (CR) and non-CR groups were performed using Wilcoxon rank-sum tests with effect size estimation. Results: Five of 15 patients achieved CR (33.3%). Baseline SIRI was significantly lower in the CR group than in the non-CR group (median 70.7 vs. 120.2; p = 0.03), with a large effect size (r = 0.55). In contrast, baseline composite nutritional indices and other inflammatory markers showed no significant association with treatment response. Nutritional status remained stable after NIR-PIT, as reflected by preserved nutritional index values. SIRI tended to increase post-treatment in patients who achieved CR. Conclusions: NIR-PIT achieved encouraging local tumor responses in recurrent HNSCC while preserving early nutritional status. Baseline SIRI may represent a potential inflammation-based correlate of CR, reflecting the balance between systemic inflammation and host immune status, and warrants validation in larger prospective cohorts.

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• Preliminary observations on peripheral inflammatory markers in NIR-PIT and ICI-treated recurrent head and neck squamous cell carcinoma.

  Hitoshi Hirakawa, Taro Ikegami, Hidetoshi Kinjyo, Shinya Agena, Shunsuke Kondo, Norimoto Kise, Yuki Kayo, Hironori Nakayoshi, Takahiro Miyahira, Hiroyuki Maeda, Mikio Suzuki

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     2026.02 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• Clinical, virological, and immunohistochemical features of laryngeal papilloma with low-risk human papillomavirus infection: insights from a 13-year institutional cohort.

  Hirakawa H, Ikegami T, Kise N, Kiyuna A, Kinjyo H, Kondo S, Nakasone W, Maeda H, Agena S, Suzuki M

  World journal of surgical oncology ( World Journal of Surgical Oncology )  24 ( 1 ) 6   2026.01 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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Other Papers 【 display / non-display 】

Other Papers 【 display / non-display 】

• 甲状腺分化癌における遠隔転移症例の検討

  安慶名 信也, 金城 秀俊, 上里 迅, 真栄田 裕行, 鈴木 幹男

  日本内分泌外科学会雑誌 ( (一社)日本内分泌外科学会 )  36 ( Suppl.3 ) S338 - S338   2019.09

   

• 副甲状腺悪性腫瘍を疑う臨床経過を示した甲状腺良性疾患の2症例

  上里 迅, 金城 秀俊, 安慶名 信也, 真栄田 裕行, 鈴木 幹男

  日本内分泌外科学会雑誌 ( (一社)日本内分泌外科学会 )  36 ( Suppl.3 ) S338 - S338   2019.09

   

• 肺癌患者における開胸下肺葉切除と頸部操作による腺腫様甲状腺腫摘出の同時手術例

  真栄田 裕行, 嘉陽 祐紀, 金城 秀俊, 上里 迅, 安慶名 信也, 平川 仁, 鈴木 幹男

  日本内分泌外科学会雑誌 ( (一社)日本内分泌外科学会 )  36 ( Suppl.3 ) S351 - S351   2019.09  [Refereed]

   

• 超高齢者の顎下部多形型脂肪肉腫の一症例

  比嘉 朋代, 真栄田 裕行, 鈴木 幹男

  口腔・咽頭科 ( 日本口腔・咽頭科学会 )  32 ( 3 ) 249 - 249   2019.08

   

• 顎下腺腺様嚢胞癌肺転移に対するニボルマブの投与 心肺停止蘇生後における使用経験

  嘉陽 祐紀, 真栄田 裕行, 上里 迅, 比嘉 朋代, 杉田 早知子, 鈴木 幹男

  口腔・咽頭科 ( 日本口腔・咽頭科学会 )  32 ( 3 ) 241 - 241   2019.08

   

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Grant-in-Aid for Scientific Research 【 display / non-display 】

Grant-in-Aid for Scientific Research 【 display / non-display 】

• Development of novel minimally invasive therapy in head and neck cancer

  Grant-in-Aid for Scientific Research(C)

  Project Year: 2024.04  -  2028.03 

  Direct: 3,700,000 (YEN)  Overheads: 4,810,000 (YEN)  Total: 1,110,000 (YEN)

• Development of minimally invasive treatment in head and neck cancer focused on PI3K/Akt/mTOR pathway

  Grant-in-Aid for Scientific Research(C)

  Project Year: 2021.04  -  2024.03 

  Direct: 3,200,000 (YEN)  Overheads: 4,160,000 (YEN)  Total: 960,000 (YEN)

• Biomarker in relation to diagnosis and prognosis in patients with HPV-related head and neck cancer

  Grant-in-Aid for Scientific Research(C)

  Project Year: 2017.04  -  2020.03 

  Investigator(s): Suzuki Mikio 

  Direct: 3,500,000 (YEN)  Overheads: 4,550,000 (YEN)  Total: 1,050,000 (YEN)

  　View Summary

  The aim of the present study is to contribute the diagnosis and risk classification of human papillomavirus (HPV) related head and neck cancer. The major achievements of the present study are as follows, The 8th edition of the AJCC staging manual reflects the prognosis of OPSCC using p16 immunoreactivity for the detection of HPV-mediated OPSCC. The discordance between p16 overexpression and the presence of HPV DNA in relation to survival outcome should be clarified to design a de-escalation study.Laryngeal cancer (LC) patients with HPV infection and high levels of p16 expression might have an improved survival outcome; however, it is necessary to recruit additional LC cases with HPV infection to determine the definitive characteristics of HPV-mediated LC and estimate survival outcome. These results may contribute to the development of a useful method for selecting patients with a potentially fair response to treatment and ensure laryngeal preservation.

• Grant-in-Aid for Scientific Research(C)

  Project Year: 2015.04  -  2018.03 

  Direct: 3,700,000 (YEN)  Overheads: 1,110,000 (YEN)  Total: 4,810,000 (YEN)

• Grant-in-Aid for Scientific Research(C)

  Project Year: 2015.04  -  2018.03 

  Direct: 3,700,000 (YEN)  Overheads: 4,810,000 (YEN)  Total: 1,110,000 (YEN)

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