有光 暁 (アリミツ サトル)

Arimitsu Satoru

写真a

職名

助教

科研費研究者番号

30546982

現在の所属組織 【 表示 / 非表示

  • 専任   琉球大学   理学部   海洋自然科学科   助教  

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  •  
    -
    2008年

    University of Louisville  その他の研究科  その他  その他

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  •  -  修士(工学科学)  工学科学

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  • 2011年10月
    -
    継続中

      琉球大学 理学部 海洋自然科学科 助教  

研究キーワード 【 表示 / 非表示

  • 有機化学

研究分野 【 表示 / 非表示

  • ナノテク・材料 / 基礎物理化学

主たる研究テーマ 【 表示 / 非表示

  • 新規有機合成法の開発

論文 【 表示 / 非表示

  • Enantioselective Fluorination of α-Branched β-Ynone Esters Using a Cinchona-Based Phase-Transfer Catalyst.

    Arimitsu S, Iwasa S, Arakaki R

    The Journal of organic chemistry   85 ( 19 ) 12804 - 12812   2020年10月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    Herein, we report the fluorination of α-branched β-ynone esters to afford their corresponding quaternary fluorinated products with good enantioselectivity (ee = 73-90%) using a cinchona-based phase-transfer catalyst. α-Branched β-ynone esters possess a highly acidic α-proton and form their corresponding enolate as a single isomer, which allows the enantioselective fluorination reaction to occur under standard cinchona-based phase-transfer catalyst conditions. Moreover, the obtained α-fluorinated product can be treated with [(SPhos)AuNTf2] (1 mol %) to afford a fluorinated 3,5-diketo carboxylic acid.

  • One-Pot Synthesis of Spiro-isobenzofuran Compounds <i>via</i> the Sequential Condensation/Oxidation Reaction of Ninhydrin with 4-Amino-1,2-naphthoquinones/2-Amino-1,4-naphthoquinones under Mild Conditions.

    Mousavi SH, Mohammadizadeh MR, Roshan Z, Jamaleddini A, Arimitsu S

    ACS omega ( AMER CHEMICAL SOC )  5 ( 29 ) 18273 - 18288   2020年07月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    Copyright © 2020 American Chemical Society. A one-pot route for the synthesis of spiro-isobenzofuran compounds was developed via the condensation reaction of ninhydrin with 4-amino-1,2-naphthoquinones or 2-amino-1,4-naphthoquinones in acetic acid followed by the oxidative cleavage of the corresponding vicinal diols at room temperature. Various derivatives of spiro[benzo[g]indole-2,1′-isobenzofuran]-3,3′,4,5(1H) tetraones and spiro[benzo[f]pyrrolo[2,3-h]quinoxaline-2,1′-isobenzofuran]-3,3′(1H)-diones were synthesized in good to high yields. Moreover, further condensation of spiro[benzo[g]indole-2,1′-isobenzofuran]-3,3′,4,5(1H)-tetraones with 1,2-diamines resulted in the new spiro-isobenzofuran compounds having phenazine rings in high yields.

  • Improvement of primary-amine-catalyzed asymmetric α-benzoyloxylation of α-branched enals by a synergistic effect of water and sulfonic acids

    Satoru Arimitsu, Emi Gima

    Tetrahedron Letters ( Tetrahedron Letters )  61 ( 25 )   2020年06月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    © 2020 Elsevier Ltd The asymmetric α-benzoyloxylation of α-branched enals developed by List was reinvestigated to further improve its reaction efficiency and enantioselectivity. After optimizing the reaction conditions, the synergistic effect of water and sulfonic acid in DMSO was revealed. The reaction efficiency was improved reducing the reaction time, and moderate enantioselectivities (up to 81% ee) with excellent E selectivity (E/Z = >20/1) were achieved. Although regioselectivity was not as high (α/γ = 1/1–6/1), α-regioisomer 2a was successfully applied to synthesize high stereo-control compounds consisting of an oxygenated quaternary carbon with two allylic units (E/Z = 20/1, 20/1).

  • Metal-free syntheses of new azocinesviaaddition reactions of enaminones with acenaphthoquinone followed by oxidative cleavages of the corresponding vicinal diols

    S. Hekmat Mousavi, Mohammad Reza Mohammadizadeh, Satoru Arimitsu, Dariush Saberi, Samira Poorsadeghi, Kojya Genta

    RSC Advances ( ROYAL SOC CHEMISTRY )  10 ( 35 ) 20552 - 20557   2020年05月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    © The Royal Society of Chemistry 2020. A one-pot, clean and green procedure is described for the syntheses of new azocine derivativesviaaddition reactions of enaminones with acenaphthoquinone followed by periodic acid-mediated oxidative cleavages of the corresponding vicinal diols. Various derivatives of azocine were prepared and well characterized. The excellent yields, simple synthesis procedure, lack of a need to carry out any tedious work-up and column chromatography, metal-free catalysis, and mild reaction conditions are important features of this protocol.

  • Preparation of Enantiomerically Pure β,β-Diaryl β-Hydroxy-α-Amino Acids and Evaluation of Their Potential as Organocatalysts

    Satoru Arimitsu, Koki Oshiro, Katsuki Endo, Emi Gima, Samira Poorsadeghi

    Asian Journal of Organic Chemistry ( Asian Journal of Organic Chemistry )  9 ( 2 ) 238 - 241   2020年02月 [ 査読有り ]

    掲載種別: 研究論文(学術雑誌)

     概要を見る

    © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim A general synthetic procedure was developed for enantiomerically pure β,β-diaryl β-hydroxy-α-amino acids 5, starting from readily available oxazolidine ester 1 and a wide variety of Grignard reagents. The problematic oxidative decomposition of β-aminodiols 3, due to their instability in the presence of metallic oxidants, was successfully suppressed using Parikh-Doering oxidation and subsequent Pinnick oxidation. Additionally, the organocatalytic ability of β,β-diaryl β-hydroxy-α-amino acids 5 was evaluated with respect to asymmetric fluorination of 2-phenylpropionaldehyde 6, and moderate enantioselectivity, 61%, was achieved using compound 5 f.

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研究発表等の成果普及活動 【 表示 / 非表示

  • Fluorination of dienamine catalysis and applicaitons

    有光 暁

    France-Japan Joint Forum on Organofluorine Chemistry for Future Pharmaceutical/Agricultural and Material Sciences  2019年11月  -  2019年11月   

  • 高付加価値フッ化ビルディングブロックの創製と応用

    有光 暁

    第9回フッ素若手の会  2019年09月  -  2019年09月   

  • Cinchona-based primary amine catalyzed a proximal fluorination of dienamines: Importance of C-H hydrogen bonding for stereoselectivity

    有光 暁

    1st International Conference on Noncovalent Interaction  2019年09月  -  2019年09月   

  • エノール化する不飽和アルデヒドを用いた新規有機触媒反応

    有光 暁

    第2回有機合成若手講演会  2018年01月  -  2018年01月   

  • Stereoselective synthesis of highly substituted allylic fluorides using organocatalysts and their applications

    有光 暁

    University of Valencia  2016年12月  -  2016年12月   

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