Yonemoto Koji

写真a

Title

Professor

Researcher Number(JSPS Kakenhi)

90398090
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Current Affiliation Organization 【 display / non-display 】

  • Duty   University of the Ryukyus   Faculty of Medicine   Health Sciences   Professor  

  • Concurrently   University of the Ryukyus   Graduate School of Health Sciences   Division of Health Sciences   Professor  

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Research Areas 【 display / non-display 】

  • epidemiology

  • Natural Science / Applied mathematics and statistics

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Published Papers 【 display / non-display 】

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Other Papers 【 display / non-display 】

  • Identifying a Dietary Pattern Associated with Metabolic Syndrome by Reduced Rank Regression in Japanese Male Workers

    Akiko Hata, Koji Yonemoto, Nanako Aki, Tohru Sakai, Emi Shuto, Takayuki Nakao, Masashi Miyoshi, Makoto Funaki

    DIABETES   65   A604 - A605   2016.06

     

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Grant-in-Aid for Scientific Research 【 display / non-display 】

  • tissue distribution and toxic mechanism of indium nano particles

    Grant-in-Aid for Scientific Research(B)

    Project Year: 2016.04  -  2019.03 

    Investigator(s): Tanaka Akiyo 

    Direct: 12,700,000 (YEN)  Overheads: 16,510,000 (YEN)  Total: 3,810,000 (YEN)

    　View Summary

    To clarify health effects of indium nanoparticles, we studied animal experiment using rats. Rats received a dose of 10 mg In/kg of indium nanoparticles (In Metal:In(OH)3;8:2, mean diameter: 6 nm) or indium oxide(In2O3, mean diameter:150 nm) once intratracheally . A subset of rats was euthanized periodically throughout the study from 1 day to 36 weeks after a treatment. The indium concentration each organ in the both groups gradually increased over time until 36 weeks. The levels of indium in the organs in the In nano group was higher than that in the In2O3 group during observation period. The severity of lung lesions in the In nano group was more severe in comparison with the In2O3 group. Furthermore, indium nanoparticles were detected in the bladder urine of rats. It is necessary to consider the effects of exposure to indium nanoparticles in humans, and precautions against such exposure are paramount with regard to health management.

  • Development of an innovative method to modify life style using a dietary pattern score

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2016.04  -  2019.03 

    Investigator(s): FUNAKI Makoto 

    Direct: 3,600,000 (YEN)  Overheads: 4,680,000 (YEN)  Total: 1,080,000 (YEN)

    　View Summary

    Appropriate diet is indispensable to prevent an onset of metabolic syndrome. Intensive studies have been made to reveal the type of food favorable/unfavorable to develop metabolic syndrome. However, meals are composed of multiple types of foods and avoiding/choosing certain types of foods will affect the intake of other types of foods, as well. Therefore, to determine if some diets are favorable/unfavorable to an onset of metabolic syndrome, it is crucial to elucidate a dietary pattern associated with an onset of metabolic syndrome and establish a method to evaluate how close/distant a certain meal is to/from such a dietary pattern. In this study, we succeeded in establishing a dietary pattern, which is associated with an onset of metabolic syndrome, and made a formula to score the distance between certain dietary patterns and the one associated with developing metabolic syndrome. This score will enable to assess the risk of developing metabolic syndrome from a dietary pattern.

  • Development of an innovative method to modify life style using a dietary pattern score

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2016.04  -  2019.03 

    Investigator(s): FUNAKI Makoto 

    Direct: 3,600,000 (YEN)  Overheads: 4,680,000 (YEN)  Total: 1,080,000 (YEN)

    　View Summary

    Appropriate diet is indispensable to prevent an onset of metabolic syndrome. Intensive studies have been made to reveal the type of food favorable/unfavorable to develop metabolic syndrome. However, meals are composed of multiple types of foods and avoiding/choosing certain types of foods will affect the intake of other types of foods, as well. Therefore, to determine if some diets are favorable/unfavorable to an onset of metabolic syndrome, it is crucial to elucidate a dietary pattern associated with an onset of metabolic syndrome and establish a method to evaluate how close/distant a certain meal is to/from such a dietary pattern. In this study, we succeeded in establishing a dietary pattern, which is associated with an onset of metabolic syndrome, and made a formula to score the distance between certain dietary patterns and the one associated with developing metabolic syndrome. This score will enable to assess the risk of developing metabolic syndrome from a dietary pattern.

  • Development of methodology for science of lifestyle habits in epidemiological research

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2016.04  -  2019.03 

    Investigator(s): Yonemoto Koji 

    Direct: 3,600,000 (YEN)  Overheads: 4,680,000 (YEN)  Total: 1,080,000 (YEN)

    　View Summary

    In the development of methodology for analysis of dietary habits data, the problems of existing methods of dietary pattern extraction related to disease onset were organized and new methods were developed. When the method was applied to the data of the population of Tokushima prefecture, we could extract the dietary pattern related to the onset of metabolic syndrome. The exercise habits data revealed how physical activity habits in the Japanese are changing by analyzing the amount of physical activity measured in the same group at two points in 2009 and 2012. Furthermore, it is important to recommend not only increasing exercise but also reducing sitting time.

  • tissue distribution and toxic mechanism of indium nano particles

    Grant-in-Aid for Scientific Research(B)

    Project Year: 2016.04  -  2019.03 

    Investigator(s): Tanaka Akiyo 

    Direct: 12,700,000 (YEN)  Overheads: 16,510,000 (YEN)  Total: 3,810,000 (YEN)

    　View Summary

    To clarify health effects of indium nanoparticles, we studied animal experiment using rats. Rats received a dose of 10 mg In/kg of indium nanoparticles (In Metal:In(OH)3;8:2, mean diameter: 6 nm) or indium oxide(In2O3, mean diameter:150 nm) once intratracheally . A subset of rats was euthanized periodically throughout the study from 1 day to 36 weeks after a treatment. The indium concentration each organ in the both groups gradually increased over time until 36 weeks. The levels of indium in the organs in the In nano group was higher than that in the In2O3 group during observation period. The severity of lung lesions in the In nano group was more severe in comparison with the In2O3 group. Furthermore, indium nanoparticles were detected in the bladder urine of rats. It is necessary to consider the effects of exposure to indium nanoparticles in humans, and precautions against such exposure are paramount with regard to health management.

display all >>

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