SHIMATA Keita

写真a

Title

Assistant Professor

Current Affiliation Organization 【 display / non-display

  • Duty   University of the Ryukyus   Graduate School of Medicine   Assistant Professor  

University 【 display / non-display

  • 2003
    -
    2009

    Kumamoto University   Faculty of Medicine   Graduated

Graduate School 【 display / non-display

  • 2016
    -
    2020

    Kumamoto University  Graduate School, Division of Medicine  Doctor's Course  Accomplished credits for doctoral program

External Career 【 display / non-display

  • 2019.04
    -
    2020.03

     

  • 2021.04
    -
    2024.04

    Kumamoto University  

  • 2024.04
     
     

    University of the Ryukyus  

Affiliated academic organizations 【 display / non-display

  •  
     
     
     

    International Liver Transplantation Societry 

Research Interests 【 display / non-display

  • 肝障害・肝再生時の好中球動態

  • Liver transplantation

  • Acute liver failure

  • SOX9

  • 腸内細菌叢

Research Areas 【 display / non-display

  • Life Science / Digestive surgery

Published Papers 【 display / non-display

  • Clinical Significance of Grade A Small-for-size Syndrome After Living Donor Liver Transplantation Utilizing the New Definition of Diagnostic Criteria: An International Multicenter Study.

    Jo HS, Kim DS, Gunasekaran V, Krishnamurthy J, Toshima T, Takahashi R, Kim JY, Krishnan SK, Okumura S, Hara T, Shimata K, Haruki K, Minnee RC, Rammohan A, Gupta S, Yoshizumi T, Ikegami T, Lee KW, Rela M

    Transplantation ( Transplantation )  109 ( 2 ) e92 - e100   2025.02 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Right Posterior Segment Graft in Adult Living-Donor Liver Transplantation: A Report of 17 Years of Experience at a Single Institution

    Kadohisa M.

    Experimental and Clinical Transplantation ( Experimental and Clinical Transplantation )  22 ( 10 ) 786 - 793   2024.10 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    OBJECTIVES: The right posterior segment graft can be selected in cases where neither the right nor left lobe graft satisfies the selection criteria for adult living donor liver transplant. However, vascular and biliary anatomy may cause technical difficulties in procurement of posterior segments in donors of living donor liver transplant and may require specific attention in vascular and biliary reconstruction in the recipient. In this study, we examined the feasibility of right posterior segment grafts in adult living donor liver transplants through donor safety and recipient outcomes and clarified the anatomic points of the surgical technique. MATERIALS AND METHODS: We retrospectively reviewed 296 cases of adult living donor liver transplants treated at Kumamoto University between August 2000 and March 2017. RESULTS: Among 296 cases, graft types were right lobe (n = 162), left lobe (n = 119), and right posterior segments (n = 9). Among donors, no significant differences were shown in operative time, blood loss, or incidence of postoperative complications between early and late phases among the 3 groups. Four cases ofright posterior segment had >2 biliary duct stumps, and 2 cases had 2 portal vein stumps. Among recipients, median actual graft-to-recipient weight ratio was 0.82% (range, 0.52%-1.22%), with no factors, including graft type, significantly associated with graft survival. Hepatic artery thrombosis and rupture of hepatic artery pseudoaneurysm occurred in 1 case as an early complication, and biliary anastomotic stricture occurred in 4 cases as a late complication. CONCLUSIONS: The right posterior segment graft may be an effective alternative in living donor liver transplant when no eligible candidates for conventional grafts are available among families and relatives. Careful preoperative anatomic evaluations and simulations are important.

  • Portal vein stenting blocked the inflow tract and completely resolved bile duct varices, formed by cavernous transformation of the portal vein

    Matsubara D.

    Clinical Journal of Gastroenterology ( Clinical Journal of Gastroenterology )    2024.08 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    There is no established treatment for bleeding bile duct varices (BDVs). We report the first case of portal vein (PV) stenting completely eradicating bleeding BDVs. A 70-year-old male with malignant lymphoma developed BDVs due to PV obstruction, which had caused compression and stricture of the distal bile duct. Endoscopic retrograde cholangiography was performed to evaluate the stricture and bleeding from the ruptured BDV was observed. Endoscopic hemostasis was difficult, requiring reopening of the extra-hepatic PV and reducing the blood flow to the BDVs for hemostasis. Therefore, PV stenting was performed. During the procedure, portal angiography confirmed an inflow tract to the BDVs. Therefore, covered stents were placed in the PV and adjusted to block the inflow tract to the BDVs at the distal end. After stenting, the BDVs were successfully blocked and all PV blood flowed through the stent placed in the extra-hepatic PV. Two weeks after stenting, the BDVs had disappeared completely and the bleeding has not recurred for months. We experienced a case in which PV stenting not only reopened an obstructed PV but also successfully occluded the inflow tract. This case demonstrates the potential of PV stenting for the treatment of hemorrhagic BDVs.

  • Corrigendum to 'A novel scoring system to predict short-term mortality after living donor liver transplantation for acute liver failure' American Journal of Transplantation, Available online 29 April 2024, In Press, Corrected Proof.

    Shimata K, Yoon YI, Hibi T, Morinaga J, Narayanan AK, Toshima T, Ito T, Akamatsu N, Kotera Y, Hong SK, Hasegawa Y, Umeda Y, Reddy MS, Ong AL, Sivaprasadan S, Varghese J, Sugawara Y, Chen CL, Nakayama N, Mochida S, Tanaka A, Suh KS, Ikegami T, Lee KW, Lee SG, Vanguard Multicenter Study of International Living Donor Liver Transplantation (iLDLT) Group

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons ( American Journal of Transplantation )    2024.08 [ Peer Review Accepted ]

    Type of publication: Research paper (other science council materials etc.)

  • Feasible living donor liver transplantation for patients on chronic hemodialysis: a multicenter study in East Asian countries.

    Kenei Furukawa, Kwang-Woong Lee, Keita Shimata, Takashi Ito, Takeo Toshima, Nobuhisa Akamatsu, Taizo Hibi, Suk Kyun Hong, Jong Man Kim, Etsuro Hatano, Tomoharu Yoshizumi, Toru Ikegmi, Kyung-Suk Suh

    Surgery today   54 ( 5 ) 471 - 477   2024.05 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    PURPOSES: End-stage liver and kidney disease is an indication for simultaneous liver and kidney transplantation. However, in countries where deceased donor transplantation is not well established, living donor liver transplantation (LDLT) is a realistic option for patients on hemodialysis (HD). We investigated the outcomes of LDLT for patients on HD. METHODS: We conducted a retrospective multicenter survey of patients on chronic HD who underwent LDLT in East Asian countries. The characteristics of donors and recipients and the short and long-term outcomes were analyzed. RESULTS: Between 2001 and 2021, 45 patients on HD underwent LDLT and 11 of these patients also underwent kidney transplantation (KT). The overall survival rate at 5 years of the 34 patients who underwent only LDLT was 44.5%. Multivariate analysis identified a low graft recipient weight ratio (< 1%) (p = 0.048) and long HD duration (≥ 10 years) (p = 0.046) as independent predictors of poor overall survival. The major complication was posttransplant bleeding, which occurred in12 patients (35%). CONCLUSION: It is important to establish the indications for LDLT, taking into consideration graft size and HD duration in candidate patients on HD.

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Other Papers 【 display / non-display

Grant-in-Aid for Scientific Research 【 display / non-display

  • Elucidation of spatiotemporal changes and conversion mechanisms of neutrophil subtypes during liver injury and regeneration

    Grant-in-Aid for Early-Career Scientists

    Project Year: 2023.04  -  2026.03 

    Direct: 3,500,000 (YEN)  Overheads: 4,550,000 (YEN)  Total: 1,050,000 (YEN)

Media Coverage 【 display / non-display

  • 生体肝移植について  TV or radio program

    ぎのわんシティFM  2025.9

    Author: Myself 

     View Summary

    生体肝移植について