Shimabukuro Wataru

写真a

Title

Assistant Professor
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Current Affiliation Organization 【 display / non-display 】

  • Duty   University of the Ryukyus   Hospital   Assistant Professor  

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  • Protocol for the nationwide registry of patients with polycystic kidney disease: japanese national registry of PKD (JRP)

    Nakatani, S; Kawano, H; Sato, M; Hoshino, J; Nishio, S; Miura, K; Sekine, A; Suwabe, T; Hidaka, S; Kataoka, H; Ishikawa, E; Shimazu, K; Uchiyama, K; Fujimaru, T; Moriyama, T; Kurashige, M; Shimabukuro, W; Hattanda, F; Kimura, T; Ushio, Y; Manabe, S; Watanabe, H; Mitobe, M; Seta, K; Shimada, Y; Kai, HRYS; Katayama, K; Ichikawa, D; Hayashi, H; Hanaoka, K; Mochizuki, T; Nakanishi, K; Tsuchiya, K; Horie, S; Isaka, Y; Muto, S

    CLINICAL AND EXPERIMENTAL NEPHROLOGY ( Clinical and Experimental Nephrology )  28 ( 10 ) 1004 - 1015   2024.10 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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  • Renal coloboma syndrome/dominant optic atrophy with severe retinal atrophy and de novo digenic mutations in <i>PAX2</i> and <i>OPA1</i>

    Shimabukuro, W; Chinen, Y; Imanaga, N; Yanagi, K; Kaname, T; Nakanishi, K

    PEDIATRIC NEPHROLOGY ( Pediatric Nephrology )  39 ( 8 ) 2351 - 2353   2024.08 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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  • Role of Iron in Children With Immunoglobulin A Nephropathy and Macrohematuria-Induced Acute Kidney Injury

    Ishimori, S; Horinouchi, T; Yamamura, T; Fujimura, J; Kamiyoshi, N; Kaito, H; Tanaka, Y; Matsukura, H; Shimabukuro, W; Shima, Y; Kawaguchi, A; Araki, Y; Nakanishi, K; Hara, S; Nozu, K

    KIDNEY INTERNATIONAL REPORTS ( Kidney International Reports )  9 ( 6 ) 1664 - 1673   2024.06 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Relationship between the serum creatinine concentrations of preterm neonates within 24 h of birth and their mothers before delivery

    Shimabukuro, W; Nakada, S; Shimada, K; Tsukayama, M; Hamada, K; Goya, H; Kinjo, N; Yoshida, T; Mekaru, K; Nakanishi, K

    CLINICAL AND EXPERIMENTAL NEPHROLOGY ( Clinical and Experimental Nephrology )  28 ( 4 ) 293 - 299   2024.04 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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  • Factors related to recurrence of proteinuria in childhood IgA nephropathy

    Shima, Y; Mukaiyama, H; Tanaka, Y; Shimabukuro, W; Nozu, K; Kaito, H; Tanaka, R; Sako, M; Iijima, K; Tokuhara, D; Yoshikawa, N; Nakanishi, K

    PEDIATRIC NEPHROLOGY ( Pediatric Nephrology )  39 ( 2 ) 463 - 471   2024.02 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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    <h4>Background</h4>Proteinuria remission is the most significant predictive factor for kidney outcome in childhood IgA nephropathy (c-IgAN). Even if proteinuria remission can be obtained, some patients have recurrence of proteinuria in the long-term.<h4>Methods</h4>This is a retrospective analysis of 312 cases of proteinuria remission among 538 consecutive children with biopsy-proven IgAN from 1976 to 2013. To elucidate the incidence and factors related to recurrence of proteinuria in c-IgAN, we compare clinical and pathological findings between patients with and without recurrence of proteinuria.<h4>Results</h4>Among 312 patients with remission of proteinuria, 91 (29.2%) had recurrence of proteinuria within the observation period (median 8 years). Using a multivariate Cox regression analysis, significant factors associated with recurrence of proteinuria were onset age (HR 1.13 [95%CI: 1.05-1.22], P = 0.002) and presence of hematuria after proteinuria remission (HR 2.11 [95%CI: 1.30-3.45], P = 0.003). The Kaplan-Meier analysis showed significant differences in CKD G3a-G5-free survival between the patients with no-recurrence of proteinuria, recurrence of proteinuria and non-proteinuria remission (P < 0.0001, log-rank test). Kidney survival was 100% in no-recurrence of proteinuria, 92.2% in recurrence of proteinuria, and 65.6% in non-proteinuria remission at 15 years. Cox analyses adjusted by proteinuria remission showed that recurrence of proteinuria (HR 03.10e<sup>9</sup> [95%CI: NA], P = 0.003) was a significant factor associated with progression to CKD G3a-G5 in all patients with c-IgAN.<h4>Conclusions</h4>Approximately 30% of patients with proteinuria remission had recurrence of proteinuria regardless of treatment. Both remission and recurrence of proteinuria are significant prognostic factors for kidney outcome. A higher resolution version of the Graphical abstract is available as Supplementary information.

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