Makino Wataru

写真a

Title

Assistant Professor

Current Affiliation Organization 【 display / non-display

  • Duty   University of the Ryukyus   Graduate School of Medicine   Assistant Professor  

University 【 display / non-display

  • 2008.04
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    2013.03

    University of the Ryukyus   Faculty of Medicine   School of Medicine   Graduated

External Career 【 display / non-display

  • 2021.04
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    2023.08

    Yuuai Medical Center  

  • 2023.09
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    2025.08

    Central Japan International Medical Center  

  • 2025.09
     
     

    Graduate School of Medical Science, University of the Ryukyus  

Affiliated academic organizations 【 display / non-display

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    Japan Society for Head and Neck Cancer 

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    Japanese Society for Radiation Oncology 

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    Japan Radiation Society 

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    Japanese Society of Interventional Radiology 

Research Interests 【 display / non-display

  • Brachytherapy

  • Intra-arterial chemotherapy

  • Radiation oncology, Intra-arterial chemotherapy, Brachytherapy

Research Areas 【 display / non-display

  • Radiation oncology, Intra-arterial chemotherapy, Brachytherapy

Published Papers 【 display / non-display

  • Non-thrombotic pulmonary emboli: imaging findings and differential diagnoses.

    Tsuchiya N, Chinen Y, Yumoto K, Uechi M, Ito J, Azama K, Makino W, Koga T, Nishie A

    Japanese journal of radiology ( Japanese Journal of Radiology )  43 ( 11 ) 1746 - 1760   2025.11 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    OBJECTIVE: Nonthrombotic pulmonary embolism (NTPE) encompasses a diverse group of rare but clinically significant conditions that involve fat, tumor, air, amniotic fluid, septic, parasitic, and iatrogenic emboli. This review summarizes the pathophysiology, imaging findings, and differential diagnoses of NTPE toward the goal of facilitating its accurate radiologic diagnosis. CONTENT: In NTPE, the use of computed tomography pulmonary angiography (CTPA) may reveal filling defects in the pulmonary arteries; however, the embolus is often not directly visualized, especially in cases of microscopic emboli. NTPE-related pulmonary lesions arise from two mechanisms: mechanical obstruction and chemical injury. Clarifying the link between these mechanisms and imaging features is crucial for achieving the accurate diagnosis of NTPEs. Tools such as dual-energy CT and ventilation-perfusion scintigraphy contribute to the detection of microvascular involvement. We present the characteristic imaging patterns and diagnostic pitfalls for each NTPE subtype, illustrated with representative cases. CONCLUSION: The awareness of NTPE entities and their imaging features is essential for the timely diagnosis and management of these emboli. Radiologists should consider the possible presence of an NTPE in patients with unexplained respiratory symptoms, especially when conventional imaging fails to demonstrate thrombotic emboli.

  • Superficial Temporal Artery-Based ReMAP: A Case Report Series in Head and Neck Cancer Intra-Arterial Chemotherapy.

    Wataru Makino, Nobukazu Fuwa, Akira Matsumoto, Shinichi Ogawa, Yoshihito Matsui, Miwako Nomura, Yutaka Toyomasu, Akinori Takada

    Head & neck     2025.05 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    BACKGROUND: Intra-arterial chemotherapy (IAC) can be highly effective for advanced head and neck cancers but often necessitates complex procedures and prolonged hospitalization. Herein, we demonstrate the utility of the repeatable microcatheter access port (ReMAP) system for streamlining IAC. METHODS: Two patients with advanced head and neck cancers underwent repeated IAC via a subcutaneously implanted ReMAP. Procedural feasibility, safety, and clinical outcomes were assessed and compared to conventional techniques. RESULTS: Case 1 involved a 42-year-old male with advanced maxillary sinus carcinoma who received eight IAC sessions of high-dose cisplatin without complications. Follow-up imaging confirmed complete tumor resolution. Case 2 was a 52-year-old female with primary intraosseous squamous cell carcinoma of the jaw who completed eight IAC sessions via an external carotid arterial sheath, then four sessions with the ReMAP, reducing inpatient requirements, and achieving tumor control. CONCLUSIONS: The ReMAP system enabled safe and effective IAC administration while reducing patient burden.

  • 上顎洞癌に対してReMAPシステムを用いて動注を行った1例(A Case of Maxillary Sinus Carcinoma Treated with Intra-Arterial Infusion Using the ReMAP System)

    Makino Wataru, Fuwa Nobukazu, Matsumoto Akira, Matsui Yoshihito

    日本インターベンショナルラジオロジー学会雑誌 ( (一社)日本インターベンショナルラジオロジー学会 )  40 ( Suppl. ) 253 - 253   2025.05 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Definitive radiotherapy consisting of whole pelvic radiotherapy with no central shielding and CT-based intracavitary brachytherapy for cervical cancer: feasibility, toxicity, and oncologic outcomes in Japanese patients (vol 25, pg 1977, 2022)

    Kusada, T; Toita, T; Ariga, T; Kudaka, W; Maemoto, H; Makino, W; Ishikawa, K; Heianna, J; Nagai, Y; Aoki, Y; Murayama, S

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY ( International Journal of Clinical Oncology )  28 ( 3 ) 491 - 491   2023.03 [ Peer Review Accepted ]

    Type of publication: Research paper (other science council materials etc.)

  • Therapeutic efficacy of intra-arterial docetaxel and nedaplatin infusion concomitant with radiotherapy for T4 maxillary sinus squamous cell carcinoma

    Heianna, J; Makino, W; Hirakawa, H; Yamashita, Y; Tomita, H; Murayama, S

    INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY ( International Journal of Oral and Maxillofacial Surgery )  51 ( 9 ) 1123 - 1130   2022.09 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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Other Papers 【 display / non-display

  • Non-thrombotic pulmonary emboli: imaging findings and differential diagnoses(タイトル和訳中)

    Tsuchiya Nanae, Chinen Yuma, Yumoto Kazuyoshi, Uechi Masaki, Ito Junji, Azama Kimei, Makino Wataru, Koga Tomomi, Nishie Akihiro

    Japanese Journal of Radiology ( (公社)日本医学放射線学会 )  43 ( 11 ) 1746 - 1760   2025.11  [Refereed]

     

Presentations 【 display / non-display

  • 放射線療法と肝動脈化学塞栓術の併用による腎細胞癌骨転移に関連する骨格関連イベントの減少(Concomitant radiotherapy and transarterial chemoembolization reduce skeletal-related events related to bone metastases from renal cell carcinoma)

    Heianna Joichi, Makino Wataru, Ariga Takuro, Toguchi Masafumi, Kusada Takeaki, Maemoto Hitoshi, Ishikawa Kazuki, Iraha Yuko, Murayama Sadayuki

    日本医学放射線学会学術集会抄録集  1900.01  -  1900.01