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• Evaluation of neonatal withdrawal syndrome in neonates delivered by women taking psychotropic or anticonvulsant drugs: A retrospective chart review of the effects of multiple medications and breastfeeding.

  Kanemura A, Masamoto H, Kinjo T, Mekaru K, Yoshida T, Goya H, Aoki Y

  European journal of obstetrics, gynecology, and reproductive biology   254   226 - 230   2020.09 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• Measurement of zinc concentration in blood and breast milk of a Wilson's disease patient taking zinc acetate

  Isagawa S.

  Pharmazie ( Pharmazie )  75 ( 5 ) 177 - 178   2020.05 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• A very-low-birth-weight infant with severe anemia due to fetomaternal transfusion syndrome possibly caused gastric rupture

  Higa Emi, Tobaru Yuji, Ikemiyagi Kozue, Yoshida Tomohide, Yara Asao

  Journal of Japan Society of Perinatal and Neonatal Medicine ( Japan Society of Perinatal and Neonatal Medicine )  56 ( 2 ) 305 - 308   2020 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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  <p> While the cause of neonatal gastric rupture is unclear, it is attributed to hypoxic episodes and the gastrointestinal asphyxia defense mechanism. Fetomaternal transfusion syndrome(FMT)is the transfusion of fetal blood into the maternal circulation, which can cause severe neonatal anemia. We experienced a rare case of these two diseases being complicated in a single patient. A 33-year-old woman was administered magnesium sulfate due to preterm labor at 27 weeks' gestation. At 29 weeks and 1 day of gestation, a cardiotocogram indicated a sinusoidal-pattern, so emergency caesarean section was performed. Soon after birth, the patient(birth weight 1,192g, Apgar scores 1/5/7, female)presented with extremely pale skin and low muscle tone. Her hemoglobin level was 2g/dL, and the HbF and α-fetoprotein levels in the maternal blood were elevated, and we diagnosed the patient with anemia caused by FMT. After performing a blood transfusion, her condition improved. However, the patient developed a gastric rupture at 6 days of age, and therefore an emergency operation was performed. In the present case, it is possible that the gastric rupture was caused by an association of factors such as severe anemia due to FMT, prematurity, the use of indomethacin for patent ductus arteriosus, and tube feeding.</p>

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• Early parenteral nutrition in neonates with congenital diaphragmatic hernia.

  Yoshida T, Goya H, Iida N, Arakaki M, Sanabe N, Nakanishi K

  Pediatrics international : official journal of the Japan Pediatric Society     2019.12

  Type of publication: Research paper (scientific journal)

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• Utility of combined nutritional therapy in late-preterm infants born at 34 weeks or 35 weeks of gestation

  Abe Sei, Goya Hideki, Yoshida Tomohide

  Online Journal of JSPEN ( Japanese Society for Clinical Nutrition and Metabolism )  1 ( 4 ) 227 - 235   2019 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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  <p><b>Background:</b> Preterm infants born at 34 to 36 weeks of gestation, designated late-preterm infants, are considered to be at risk of nutritional imbalance. However, nutritional management for late-preterm infants, especially those born at 34 or 35 weeks of gestation, is not clearly established.</p><p><b>Methods:</b> Subjects included 146 late-preterm infants born at 34 or 35 weeks of gestation who were admitted to our neonatal intensive care unit between January 2012 and June 2018. After classifying them into 2 groups, received combined nutritional therapy (CNT) including parenteral nutrition (CNT group) or received enteral nutrition(enteral nutrition group), we retrospectively compared nutritional management status and the effect of nutritional management on the infant's physique.</p><p><b>Results:</b> In total, 74 (97.4%) of the 76 late-preterm infants born at 34 weeks and 22 (31.4%) of the 70 late-preterm infants born at 35 weeks received CNT. Birth weight of those born at 35 weeks was significantly different between the CNT and enteral nutrition groups, but body weight at discharge was not significantly different between them. In the CNT group, body weight at discharge was similar, and physique at 3 months of age was not significantly different between those born at 34 weeks and those born at 35 weeks. No adverse events related to parenteral nutrition (PN) were observed.</p><p><b>Conclusions:</b> CNT has the potential to correct the physical developmental disparity in late-preterm infants born at 34 or 35 weeks of gestation. The introduction of PN should be considered in such cases.</p>

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