UMEMURA Masayuki

写真a

Title

Associate Professor

Researcher Number(JSPS Kakenhi)

90359985

Laboratory Address

1 Senbaru,Nishihara,Okinawa 903-0213

Mail Address

E-mail address

Homepage URL

http://w3.u-ryukyu.ac.jp/hostdefense/

2
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Current Affiliation Organization 【 display / non-display 】

  • Duty   University of the Ryukyus   Tropical Biosphere Research Center   Associate Professor  

  • Concurrently   University of the Ryukyus   Graduate School of Medicine   Division of Medical Science   Associate Professor  

  • Concurrently   University of the Ryukyus   Faculty of Medicine   Associate Professor  

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Academic degree 【 display / non-display 】

  • Nagoya University -  Doctor of Medicine

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External Career 【 display / non-display 】

  • 2001.04
    -
    2002.03

    Nagoya University, Postdoctoral Fellow  

  • 2001.05
    -
    2002.08

    Kanazawa University, Postdoctoral Fellow  

  • 2002.09
    -
    2007.03

    Gene Research Center, University of the Ryukyus, Research Associate  

  • 2007.04
    -
    2009.03

    Gene Research Center, University of the Ryukyus, Assistant Professor  

  • 2009.04
    -
    2010.03

    Center of Molecular Biosciences, University of Ryukyus, Assistant Professor  

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Affiliated academic organizations 【 display / non-display 】

  • 2003.04
    -
    Now
     

    The American Association of Immunologists 

  • 1997.04
    -
    Now
     

    The Japanese Society for Immunology 

  • 1997.04
    -
    Now
     

    The Japanese Society for Virology 

  • 1997.04
    -
    Now
     

    Japanese Society for Bacteriology 

  • 2024.04
    -
    Now
     

    Japanese Society for Interferon and Cytokine Research 

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Research Interests 【 display / non-display 】

  • Immunology of host defense against infectious diseases

  • 感染症

  • サイトカイン

  • 生体防御

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Research Areas 【 display / non-display 】

  • Life Science / Bacteriology

  • Life Science / Immunology

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Research Theme 【 display / non-display 】

  • Analysis of immune response and protective mechanism against infections

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Published Papers 【 display / non-display 】

  • GRIM-19 is a target of mycobacterial Zn2+ metalloprotease 1 and indispensable for NLRP3 inflammasome activation.

    Kurane, T., Matsunaga, T., Ida, T., Sawada, K., Nishimura, A., Fukui, M., Umemura, M., Nakayama, M., Ohara, N., Matsumoto, S., Akaike, T., Matsuzaki, G., Takaesu, G.

    FASEB Journal   36 ( 1 ) e22096   2022.01 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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      DOI

  • Porphyromonas gingivalis components/secretions synergistically enhance pneumonia caused by Streptococcus pneumoniae in mice

    Okabe, T., Kamiya, Y., Kikuchi, T., Goto, H., Umemura, M., Suzuki, Y., Sugita, Y., Naiki, Y., Hasegawa, Y., Hayashi, J., Kawamura, S., Sawada, N., Takayanagi, Y., Fujimura, T., Higuchi, N., Mitani, A.

    International Journal of Molecular Sciences   22 ( 23 ) 12704   2021.11 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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      DOI

  • TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation

    Iizasa, E., Chuma, Y., Uematsu, T., Kubota, M., Kawaguchi, H., Umemura, M., Toyonaga, K., Kiyohara, H., Yano, I., Colonna, M., Sugita, M., Matsuzaki, G., Yamasaki S., Yoshida, H., Hara H.

    Nature Communications     2021.04 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Dispensable role of chemokine receptors in migration of mycobacterial antigen-specific CD4<sup>+</sup> T cells into Mycobacterium-infected lung.

    Matsuzaki G, Yamasaki M, Tamura T, Umemura M

    Immunobiology ( Immunobiology )  224 ( 3 ) 440 - 448   2019.05 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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      PubMed

  • Interleukin-17 family cytokines in protective immunity against infections: role of hematopoietic cell-derived and non-hematopoietic cell-derived interleukin-17s.

    Matsuzaki G, Umemura M

    Microbiology and immunology ( Microbiology and Immunology )  62 ( 1 ) 1 - 13   2018.01 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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      DOI
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      PubMed

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Other Research Activities 【 display / non-display 】

  • "U.S.-Japan Cooperative Medical Sciences Program: Mycobacterial Diseases Panel Meeting 2024" Chairperson

    Other Research Activities 

    2024.04
    　
    　

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Grant-in-Aid for Scientific Research 【 display / non-display 】

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2023.04  -   

    Investigator(s): Hiromitsu Hara  Member: Masayuki Umemura

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2023.04  -   

    Investigator(s): Kenji Toyonaga  Member: Masayuki Umemura

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2023.04  -   

    Investigator(s): Yoshikazu Naiki  Member: Masayuki Umemura

  • Analysis of type 3 immune responses against M. tuberculosis infection and application to boost vaccine

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2021.04  -   

    Investigator(s): Masayuki Umemura 

    Direct: 3,200,000 (YEN)  Overheads: 960,000 (YEN)  Total: 4,160,000 (YEN)

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2020.04  -  2023.03 

    Investigator(s): Goro Matsuzaki  Member: Masayuki Umemura

    Direct: 1,800,000 (YEN) 

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Other External funds 【 display / non-display 】

  • Project Year: 2024.04  -  2024.04 

    Direct: 500,000 (YEN)  Overheads: 0 (YEN)  Total: 500,000 (YEN)

  • Project Year: 2024.04  -  2024.04 

    Direct: 500,000 (YEN)  Overheads: 0 (YEN)  Total: 500,000 (YEN)

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SDGs 【 display / non-display 】

  • 研究テーマ「結核に対する感染防御機構の解明」

  • 県外小学生を対象とした「沖縄の自然・文化」のオンライン講座

  • 沖縄県主催「子ども科学技術人材育成事業 」等の一環教育

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Social Activity 【 display / non-display 】

  • 2005.04
    　
    　

  • 2010.04
    　
    　

  • 2005.04
    　
    　

  • 2015.04
    　
    　

  • 2024.06
    　
    　

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Media Coverage 【 display / non-display 】

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