Current Affiliation Organization 【 display / non-display 】

Current Affiliation Organization 【 display / non-display 】

Graduate School 【 display / non-display 】

Graduate School 【 display / non-display 】

External Career 【 display / non-display 】

External Career 【 display / non-display 】

display all >>

Affiliated academic organizations 【 display / non-display 】

Affiliated academic organizations 【 display / non-display 】

Research Interests 【 display / non-display 】

Research Interests 【 display / non-display 】

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

Published Papers 【 display / non-display 】

Published Papers 【 display / non-display 】

• Amoxetamide A, a new anoikis inducer, produced by combined-culture of Amycolatopsis sp. and Tsukamurella pulmonis

  Pan, CQ; Ikeda, H; Minote, M; Tokuda, T; Kuranaga, T; Taniguchi, T; Shinzato, N; Onaka, H; Kakeya, H

  JOURNAL OF ANTIBIOTICS ( Journal of Antibiotics )  77 ( 1 ) 66 - 70   2023.10 [ Peer Review Accepted ]

  Type of publication: Research paper (other science council materials etc.)

  • Access this article
    DOI
  • Search related information
    PubMed

• Microbial symbiosis in anaerobic ciliates

  Naoya Shinzato

  The CELL   55 ( 6 ) 37 - 41   2023.05

  Type of publication: Research paper (scientific journal)

• Complete Genome Sequence of "<i>Candidatus</i> Hydrogeosomobacter endosymbioticus," an Intracellular Bacterial Symbiont of the Anaerobic Ciliate Scuticociliate GW7.

  Shiohama Y, Takeshita K, Hirakata Y, Nobu MK, Ito M, Shinzato N

  Microbiology resource announcements ( Microbiology Resource Announcements )  11 ( 2 ) e0115021   2022.02 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

  　View Summary

  The bacterium “ <italic>Candidatus</italic> Hydrogenosomobacter endosymbioticus” is an intracellular symbiont of anaerobic scuticociliate GW7, which is associated with hydrogenosome together with methanogenic archaea. Here, we report a complete genome sequence of the symbiont consisting of 827 kbp. Knowing this sequence would contribute to the understanding of the metabolic interactions and evolution of the tripartite symbiosis.

  • Access this article
    DOI
  • Search related information
    PubMed

• Amycolapeptins A and B, Cyclic Nonadepsipeptides Produced by Combined-culture of <i>Amycolatopsis</i> sp. and <i>Tsukamurella pulmonis</i>.

  Pan C, Kuranaga T, Cao X, Suzuki T, Dohmae N, Shinzato N, Onaka H, Kakeya H

  The Journal of organic chemistry ( Journal of Organic Chemistry )  86 ( 2 ) 1843 - 1849   2021.01 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

  　View Summary

  Two nonapeptide natural products, amycolapeptins A (1) and B (2) with a 22-membered cyclic depsipeptide skeleton, β-hydroxytyrosine, and a highly modified side chain, which were not produced in a monoculture of the rare actinomycete Amycolatopsis sp. 26-4, were discovered in broth of its combined-culture with Tsukamurella pulmonis TP-B0596. The planar structures were elucidated by spectroscopic analyses (extensive 2D-NMR and MALDI-TOF MS/MS). The absolute configurations of component amino acids were unambiguously determined by the highly sensitive advanced Marfey's method we recently developed. Additionally, the structures of unstable/unusual moieties were corroborated by chemical synthesis and CD analysis.

  • Access this article
    DOI
  • Search related information
    PubMed

• Pseudoalteropeptide A, A Novel Lipopeptide from the Marine Bacterium Pseudoalteromonas piscicida SWA4_PA4 Isolated from Marine Seaweed

  Reiko Ueoka, Naoya Shinzato, Noritaka Kagaya, Hikaru Suenaga, Kazuo Shin-ya

  The Journal of Antibiotics   74   105 - 110   2020.10 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

display all >>

Books 【 display / non-display 】

Books 【 display / non-display 】

• Handbook of Protistorogy

  ( Part: Allotment Writing )

  2023.05

• Microbiology Monographs 19, (Endo)symbiotic methangenic archaea 2nd edition

  Shinzato N, Takeshita K, Kamagata Y ( Part: Allotment Writing ,  Methanogenic and bacterial endosymbionts of anaerobic free-living ciliates )

  Springer-Verlag, Berlin Heidelberg  2018.11

Other Papers 【 display / non-display 】

Other Papers 【 display / non-display 】

• Functional genomics of the Lactobacillus paracasei strain LC-Ikematsu isolated from the Okinawan natural environment

  Tada I, Saitoh S, Aoyama H, Shinzato N, Morita K, Yamamoto N, Ikematsu S

  Bulletin of National Institute of Technology, Okinawa College   11   1 - 8   2017.03

   

• ヒョウタンナガカメムシ類で見つかった環境獲得型細胞内共生

  竹下和貴, 松浦優, 孟憲英, 孟憲英, 三谷恭雄, 新里尚也, 菊池義智, 菊池義智

  日本応用動物昆虫学会大会講演要旨   61st   92   2017.03

   

  J-GLOBAL

• カメムシ類における垂直伝播を伴わない細胞内共生

  菊池義智, 竹下和貴, 竹下和貴, 松浦優, 孟憲英, 新里尚也, 三谷恭雄

  日本微生物生態学会大会(Web)   2017   ROMBUNNO.O‐033 (WEB ONLY)   2017

   

  J-GLOBAL

Presentations 【 display / non-display 】

Presentations 【 display / non-display 】

• Comparative analysis between bioactive compound and bacterial symbiont in marine sponges

  Tanaka S, Shirai Y, Ito M, Shinzato N

  Japan Symbiosis Society  2018.11  -  2018.11 

• 嫌気性繊毛虫におけるメタン菌、バクテリアとの共生関係

  竹下和貴, 山田尊貴, 川原邑斗, 成廣隆, 鎌形洋一, 新里尚也

  日本微生物生態学会  (沖縄コンベンションセンター, 宜野湾)  2018.07  -  2018.07 

• 沖縄微生物ライブラリーを利用した植物病原糸状菌の抑制

  上野誠, 田村朋子, Yokoyama Y, Ganphung R, 新里尚也, 伊藤通浩

  日本微生物生態学会  (沖縄コンベンションセンター, 宜野湾)  2018.07  -  2018.07 

• 沖縄産Axinella 属カイメン類の共生微生物相 - 地球の反対側との比較

  砂川春樹, Sanghwa Park, 青山洋昭, 長濱秀樹, 金本明彦, 齋藤星耕, 伊藤通浩, 新里尚也

  日本微生物生態学会  (沖縄コンベンションセンター, 宜野湾)  2018.07  -  2018.07 

Grant-in-Aid for Scientific Research 【 display / non-display 】

Grant-in-Aid for Scientific Research 【 display / non-display 】

• Grant-in-Aid for Scientific Research(B)

  Project Year: 2021.04  -  2026.03 

  Direct: 12,900,000 (YEN)  Overheads: 16,770,000 (YEN)  Total: 3,870,000 (YEN)

• Grant-in-Aid for Scientific Research(B)

  Project Year: 2021.04  -  2025.03 

• Analysis of basic metabolism of protozoa responsible for sewage treatment process and elucidation of microbial metabolism network

  Grant-in-Aid for Scientific Research(B)

  Project Year: 2017.04  -  2022.03 

  Investigator(s): Shinzato Naoya 

  Direct: 13,500,000 (YEN)  Overheads: 17,550,000 (YEN)  Total: 4,050,000 (YEN)

  　View Summary

  In the present study, we analyzed in detail the whole genome information of the bacterial symbiont TC1 living in Trimyema ciliate, which plays a major role in a sewage treatment process. As the results, it was shown that TC1 may have obtained amino acids from host ciliate and actively synthesized lipids. In addition, it was revealed that another ciliate closely related to the genus Cyclidium also have symbiotic bacteria of unknown function in addition to methanogens, which was named Hydrogenosomobacter endosymbioticus. Histochemical analysis showed that both methanogens and Hydrogenosomobacter symbiont are in close contact with hydrogen-generating organelle, hydrogenosomes.

• Grant-in-Aid for Scientific Research(B)

  Project Year: 2017.04  -  2021.03 

  Direct: 13,500,000 (YEN)  Overheads: 4,050,000 (YEN)  Total: 17,550,000 (YEN)

• Grant-in-Aid for Young Scientists(B)

  Project Year: 2010.04  -  2012.03 

  Direct: 3,100,000 (YEN)  Overheads: 930,000 (YEN)  Total: 4,030,000 (YEN)