Saito Mika

写真a

Title

Assistant Professor

Researcher Number(JSPS Kakenhi)

90235078
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Current Affiliation Organization 【 display / non-display 】

  • Duty   University of the Ryukyus   Graduate School of Medicine   Assistant Professor  

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University 【 display / non-display 】

  • 　
    -
    2004.03

    Nihon Fukushi University     Area Studies   Other

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Academic degree 【 display / non-display 】

  • Hokkaido University -  PhD

  • Hokkaido University -  Master of Veterinary Medicine

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Research Interests 【 display / non-display 】

  • Tropical Medicine,Zoonosis

  • 新興再興感染症

  • 人獣共通感染症

  • One Health

  • フラビウイルス

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Research Areas 【 display / non-display 】

  • Life Science / Veterinary medical science

  • Life Science / Hygiene and public health (laboratory)

  • Life Science / Virology

  • Life Science / Virology

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Published Papers 【 display / non-display 】

  • Kozen Yoshino's experimental infections with Taenia solium tapeworms: An experiment never to be repeated.

    Ito A, Saito M, Donadeu M, Lightowlers MW

    Acta tropica ( Acta Tropica )  205   105378   2020.05 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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  • Serologic and Virologic Studies of an Imported Dengue Case Occurring in 2014 in Okinawa, Japan

    Saito Mika, Tamayose Maki, Miyagi Kazuya, Takaragawa Hiroo, Tateyama Masao, Tadano Masayuki, Fujita Jiro

    Japanese Journal of Infectious Diseases ( 国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会 )  69 ( 1 ) 60 - 65   2016 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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    After returning from Bali, Indonesia, in February 2014, a 72-year-old man was hospitalized in Okinawa owing to a high fever and rash. Dengue was clinically suspected, and the patient tested positive for IgM against dengue using a commercial kit. Serologically, the patient showed secondary seroreactivity. Significant increases in neutralization titers (N-titers) against all 4 serotypes of dengue virus (DENV) and Japanese encephalitis virus (JEV) strains were recognized in convalescent-phase sera comparing to acute phase sera. The N-titer against DENV serotype 1 (DENV-1) was the highest among all DENV serotypes. Interestingly, the N-titers against JEV strains were significantly higher than those against all types of DENV comparing to acute phase sera. The virus was isolated from the acute-phase serum and identified as DENV-1 and designated RD14/Okinawa. The patient's symptoms were due to DENV-1 infection. Phylogenetic sequencing analysis indicated that the isolate RD14/Okinawa belonged to genotype I of DENV-1, which is closely related to the Southeast Asian strains and isolates found during the dengue outbreak in Japan in 2014. We should undertake control measures against dengue in Okinawa, which is a subtropical area with <i>Aedes albopictus</i> activity throughout year.

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  • Prevalence of Japanese encephalitis virus antibody in sika deer (<i>Cervus nippon</i>) in Odaigahara, Kii Peninsula, Japan

    SAITO Mika, ARAKI Ryota, TORII Harumi, ASAKAWA Mitsuhiko

    Japanese Journal of Zoo and Wildlife Medicine ( Japanese Society of Zoo and Wildlife Medicine )  20 ( 3 ) 41 - 45   2015 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

    　View Summary

    Sero-epidemiological study of Japanese encephalitis virus was conducted on sika deer (<i>Cervus nippon</i>) captured in Odaigahara, a forested area, on Kii peninsula, Japan, in 2009 and 2010. Nine (10.3%) out of 87 deer had neutralizing antibodies against Japanese encephalitis virus (JEV) Oki431S strain, belonging to genotype 1, a widely circulating genotype in Japan, and one (1.1%) had that against JEV Beijing-1 strain, vaccine strain, genotype 3. Prevalence rates of JEV Oki431S antibody tended to increase with age and reached 20%. This result indicates that deer are sensitive to JEV, and also strongly suggests that Odaigahara is a JEV-endemic area, with rather low virus activity.

  • Epidemiological study of Japanese encephalitis virus in Vientiane, Lao PDR, in 1990s.

    Saito M, Soukaloun D, Phongsavath K, Phommasack B, Makino Y

    TheScientificWorldJournal ( Hindawi Publishing Corporation )  2015   235934 - 12   2015 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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    Phylogenetic analysis of Japanese encephalitis virus (JEV) was conducted using core-premembrane and envelope gene sequence data of two strains from Vientiane, Lao People's Democratic Republic, in 1993 and five from Okinawa, Japan, in 2002 and 2003, and previously published strains. The two Vientiane strains designated as LaVS56 and LaVS145 belonged to genotype 1 (G1) and the same subcluster of G1 as Australian strain in 2000, Thai strains in 1982-1985 and 2004-2005, and Vietnamese strain in 2005, but were distinct from the subcluster of recently distributing G1 strains widely in Asia including Okinawan strains and recent Lao strain in 2009. These clusters with own distinct distributions indicated involvements of different mechanisms and routes of spreading viruses and clarified that Australian G1 strain is from Southeast Asia, not from East Asia. Both Vientiane strains were antigenically close to P19-Br (G1, isolate, Thailand), but distinct from Nakayama (G3, prototype strain, Japan), Beijing-1 (G3, laboratory strain, China), and JaGAr#01 (G3, laboratory strain, Japan), demonstrated by cross-neutralization tests using polyclonal antisera. These results together with seroepidemiologic study conducted in Vientiane strongly suggest that diversified JEV cocirculated there in early 1990s.

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  • Proposal for Japanese Encephalitis Surveillance Using Captured Invasive Mongooses Under an Eradication Project on Okinawa Island, Japan

    Saito M, Nakata K, Nishijima T, Yamashita K, Saito A, Ogura G

    Vector-Borne Zoonotic Dis ( その他の出版社 )  9   259 - 266   2009

    Type of publication: Research paper (scientific journal)

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Books 【 display / non-display 】

  • History of Malaria in Yaeyama Wartime Malaria and Malaria Elimination in Yaeyama Area Multilingual version (JPN, ENG, CHI, SPA)

    Mika Saito, Khew Ee Hung ( Part: Editing and Writing )

    Esri  2022.04

  • Trials for Risk Assessment of Japanese encephalitis Based on Serologic Survey of Wild Animals

    Saito M, Ito T, Amano Y, Takara J, Nakata K, Tamanaha S, Osa Y, Yohino T, Onuma M, Kuwana T, Ogura G, Tadano M, Endoh D, Asakawa M ( Part: Multiple Authorship )

    InTech Book Open Access Publisher  2011

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Presentations 【 display / non-display 】

  • THE POTENTIAL OF ON-LINE CITIZEN SCIENCE APPLICATION FOR COMMUNITY-PARTICIPATORY MONITORING OF MOSQUITOES, DEVELOPED IN THIS STUDY.

    Mika Saito, Takashi Ono, Kanna Oikawa, Masami Kaneko, Ken-Taro Sekine, Miyuki Shimabukuro

    Joint International Tropical Medicine Meeting2022  2022.12  -  2022.12 

  • Lessons Learned from the History of the Malaria Elimination in Yaeyama, Okinawa, Japan - in Order to Overcome the Era of Infectious Diseases

    Mika SAITO

    Joint International Tropical Medicine Meeting  2021.12  -  2021.12 

  • Will Citizen Science Change Human Behavior Against Infectious Disease Control

    Mika SAITO

    Joint International Tropical Medicine Meeting  2020.12  -  2020.12 

  • 蚊媒介性感染症対策におけるシチズンサイエンスの可能性—蚊の画像分類システム試作

    斉藤 美加

    第５４回日本脳炎ウイルス生態学研究会  2019.05  -  2019.05 

  • 蚊媒介性感染症から考えるシチズンサイエンスの可能性

    斉藤 美加

    琉球大学未来共創フェア  2019.03  -  2019.03 

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Grant-in-Aid for Scientific Research 【 display / non-display 】

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SDGs 【 display / non-display 】

  • 蚊媒介性感染症対策における伝統知と科学知の融合?おばあの知恵が高める災害後のレジリエンスー

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