Current Affiliation Organization 【 display / non-display 】

Current Affiliation Organization 【 display / non-display 】

External Career 【 display / non-display 】

External Career 【 display / non-display 】

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Research Interests 【 display / non-display 】

Research Interests 【 display / non-display 】

Research Areas 【 display / non-display 】

Research Areas 【 display / non-display 】

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Published Papers 【 display / non-display 】

Published Papers 【 display / non-display 】

• Evidence for endogenous rhythmicity in cirral activity of the intertidal barnacle <i>Fistulobalanus albicostatus</i>

  Katayama, A; Takekata, H; Kunita, I; Takemura, A

  SCIENTIFIC REPORTS ( Scientific Reports )  15 ( 1 ) 44100   2025.12 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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    DOI
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• Flow-Driven Fusion Edge Selection for Network Integration Inspired by Physarum polycephalum

  Megumi Uza, Itsuki Kunita

  Journal of Information and Communication Engineering   12 ( 2 ) 638 - 646   2025.12 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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    DOI

• Synergistic development model of population growth and infrastructure networks based on the slime mold network

  Uza, M; Kinjo, A; Kunita, I

  ARTIFICIAL LIFE AND ROBOTICS ( Artificial Life and Robotics )  30 ( 3 ) 523 - 533   2025.08 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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    DOI

• Four-dimensional phenotyping reveals MYOSIN XI-dependent establishment of branch morphology through upward- and stably-directed growth in Arabidopsis

  Yoshida, D; Kunita, I; Toda, M; Ueda, H; Higaki, T

  QUANTITATIVE PLANT BIOLOGY ( Quantitative Plant Biology )  6   e15   2025.06 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• Behavioral Response Model of a Ciliate <i>Paramecium</i> toObstacle Collision Based on Membrane Excitation Dynamics Driven by Chemical Gradients

  OMINE Shiho, KUNITA Itsuki

  Journal of Computer Chemistry, Japan ( Society of Computer Chemistry, Japan )  24 ( 2 ) 46 - 57   2025

  Type of publication: Research paper (scientific journal)

  　View Summary

  <p>This study aims to represent the fundamental principles of information processing systems that generate flexible behaviors in organisms using a mathematical model based on chemical gradients. Biological experiments were conducted to study the behavioral responses of the ciliate Paramecium, a unicellular organism, to collisions with obstacles. The results showed that Paramecium exhibited two distinct behaviors: one in which it changed direction immediately after the collision and another in which it moved along the obstacle before changing direction. While both behaviors had the same angle and speed at the time of collision, the sign of the angle changed before the collision. The behavior of Paramecium is controlled by the movement of cilia on its surface, which is regulated by membrane excitation dynamics driven by chemical gradients inside and outside the cell. We developed a mathematical model that links membrane excitation dynamics to observed behaviors and performed numerical simulations. The results showed that, similar to the experimental results, the two behaviors could be replicated based on the difference in the sign of the angle change before the collision. In other words, Paramecium exhibits flexibility in its behavior, producing different responses based on its motion history, even under the same chemical gradient conditions.</p>

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    CiNii Research

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Other Papers 【 display / non-display 】

Other Papers 【 display / non-display 】

• Fusion Edge Selection Method Using a Slime Mold Model

  Megumi Uza, Itsuki Kunita

  Proceedings of ICIIBMS 2026     2025.12  [Refereed]

   

• Impact of Shepherd Interaction on Flock Dynamics in MultiShepherding

  仲田圭吾, 松本晶子, 國田樹

  SCIS&ISIS 2024     2024.11  [Refereed]

   

• Relationship between the Proportion of Agents with Different Repulsion Distances and Their Spatial Arrangement

  本間野々花, 松本晶子, 國田樹

  SCIS&ISIS 2024     2024.11  [Refereed]

   

• Reforming network routes using phase changes in slime molds

  宇座恩, 國田樹

  SCIS&ISIS 2024     2024.11  [Refereed]

   

• Cellular Ethological Dynamics in Diorama Environments

  Nishigami, Y; Kunita, I; Sato, K; Nakagaki, T

  JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN ( Journal of the Physical Society of Japan )  92 ( 12 )   2023.12  [Refereed]

   

  DOI

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Presentations 【 display / non-display 】

Presentations 【 display / non-display 】

• Swimming Behavior of Coral Larvae Driven by Ciliary Motion

  Nonoka Homma, Yuhei Mori, Masaya Morita, Itsuki Kunita, Toshiyuki Nakagaki

  Oxford-Japan Symposium on Cell Behaviors in Simple to Complex Environments  2025.09  -  2025.09 

• Mathematical Modeling of the Cluster Formation Process in heterotypic cell populations

  Nonoka Homma, Itsuki Kunita

  Oxford-Japan Symposium on Cell Behaviors in Simple to Complex Environments  2025.09  -  2025.09 

• Mathematical Modeling and Simulation of the morphological Change Process in Slime Molds Driven by Environmental Adaptation

  Megumi Uza, Itsuki Kunita

  Oxford-Japan Symposium on Cell Behaviors in Simple to Complex Environments  2025.09  -  2025.09 

• Reforming network routes using phase changes in slime molds

  Megumi Uza, Itsuki Kunita

  SCIS&ISIS 2024  2024.11  -  2024.11 

• Impact of Shepherd Interaction on Flock Dynamics in MultiShepherding

  Keigo Nakada, Akiko Matsumoto-Oda, Itsuki Kunita

  SCIS&ISIS 2024  2024.11  -  2024.11 

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Academic Awards 【 display / non-display 】

Academic Awards 【 display / non-display 】

• Best Paper Award

  2015.09   The 6th Japan-China-Korea MEMS/NEMS 2015   Angiogenic sprouts form perfusable vascular networks inside multicellular spheroid

  Winner: Yuji Nashimoto, Itsuki Kunita, Akiko Nakamasu, Yusuke Torisawa, Hisako Imamura-Takigawa, Hidetoshi Kotera, Koichi Nishiyama, Takashi Miura, Ryuji Yokokawa

Grant-in-Aid for Scientific Research 【 display / non-display 】

Grant-in-Aid for Scientific Research 【 display / non-display 】

• Grant-in-Aid for Scientific Research(C)

  Project Year: 2023.04  -  2027.03 

  Direct: 3,600,000 (YEN)  Overheads: 4,680,000 (YEN)  Total: 1,080,000 (YEN)

• Grant-in-Aid for Scientific Research(C)

  Project Year: 2023.04  -  2027.03 

  Direct: 3,600,000 (YEN)  Overheads: 4,680,000 (YEN)  Total: 1,080,000 (YEN)

• Heuristic algorithm of exploration and exploitation to the space geometry in ciliates and amoebae

  Grant-in-Aid for Transformative Research Areas (A)

  Project Year: 2021.09  -  2026.03 

  Direct: 92,400,000 (YEN)  Overheads: 120,120,000 (YEN)  Total: 27,720,000 (YEN)

• Heuristic algorithm of exploration and exploitation to the space geometry in ciliates and amoebae

  Grant-in-Aid for Transformative Research Areas (A)

  Project Year: 2021.09  -  2026.03 

  Direct: 92,400,000 (YEN)  Overheads: 120,120,000 (YEN)  Total: 27,720,000 (YEN)

• Grant-in-Aid for Scientific Research(C)

  Project Year: 2019.04  -  2023.03 

  Direct: 3,400,000 (YEN)  Overheads: 4,420,000 (YEN)  Total: 1,020,000 (YEN)

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SDGs 【 display / non-display 】

SDGs 【 display / non-display 】

Amount of external funds acquired by year 【 display / non-display 】

Amount of external funds acquired by year 【 display / non-display 】

Social Activity 【 display / non-display 】

Social Activity 【 display / non-display 】

• 2025.04

  -

  2026.03