ISHIDA Akio

写真a

Researcher Number(JSPS Kakenhi)

10343378

Laboratory Address

207 Uehara,Nishihara,Okinawa

Mail Address

E-mail address

Laboratory Phone number

+81-98-895-2360

Laboratory Fax number

+81-98-895-1416

Academic degree 【 display / non-display

  • University of the Ryukyus -  Doctor of Medicine

External Career 【 display / non-display

  • 1999
    -
    2000

     

  • 2007.04
    -
    2012.03

    University of the Ryukyus, Faculty of Medicine, University Hospital, Research Associate  

  • 2020.07
     
     

    Graduate School of Medicine, University of the Ryukyus  

  • 2020.07
     
     

    Department of Cardiovascular Medicine, Nephrology and Neurology, Graduate School of Medicine, University of the Ryukyus, Associate Professor  

  • 2022.04
     
     

     

Research Interests 【 display / non-display

  • cell therapy

  • atherosclerosis

  • arteriosclerosis

  • hypertension

  • peripheral artery disease

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Research Areas 【 display / non-display

  • Life Science / Nephrology

  • Life Science / Cardiology

  • Life Science / General internal medicine

  • Life Science / Nephrology

  • Life Science / Cardiology

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Published Papers 【 display / non-display

  • Urate-lowering drugs for chronic kidney disease with asymptomatic hyperuricemia and hypertension: a randomized trial.

    Kohagura K, Satoh A, Kochi M, Nakamura T, Zamami R, Tana T, Kinjyo K, Funakoshi R, Yamazato M, Ishida A, Sakima A, Iseki K, Arima H, Ohya Y

    Journal of hypertension ( Journal of Hypertension )  41 ( 9 ) 1420 - 1428   2023.09 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • The Association of Smoking and Hyperuricemia with Renal Arteriolosclerosis in IgA Nephropathy.

    Shinzato Y, Zamami R, Oshiro N, Nakamura T, Ishida A, Ohya Y, Kohagura K

    Biomedicines   11 ( 7 )   2023.07 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Achievement rate of target blood pressure in patients with hypertension treated by hypertension specialists and non-specialists in a real-world setting.

    Sakima A, Yamazato M, Kohagura K, Ishida A, Matayoshi T, Tana T, Nakamura Y, Ohya Y

    Hypertension research : official journal of the Japanese Society of Hypertension ( Hypertension Research )    2023.07 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Association between visceral fat mass and arterial stiffness among community-based screening participants.

    Ishida A, Taira H, Shinzato T, Ohya Y

    Hypertension research : official journal of the Japanese Society of Hypertension ( Hypertension Research )    2023.06 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Acquired factor V inhibitor with erythema and eosinophilia in a patient with end-stage renal disease.

    Katsuren E, Kohagura K, Kinjyo T, Zamami R, Nakamura T, Oshiro N, Sunagawa Y, Omine K, Kudo Y, Shinzato Y, Osaki T, Souri M, Ichinose A, Yamazato M, Ishida A, Ohya Y

    CEN case reports ( CEN case reports )  12 ( 1 ) 91 - 97   2023.02 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    Autoimmune factor V deficiency (AiFVD) is a rare bleeding disorder caused by factor V inhibitors. In this report, we present the case of an 89-year-old man who developed bleeding tendency during surgery to create arteriovenous fistula for hemodialysis. The bleeding tendency developed with prolongation of activated partial thromboplastin and prothrombin time, following drug-induced eruption and eosinophilia. Significant reduction in coagulation factor activity and inhibitory pattern in cross-mixing tests suggested the presence of inhibitors to coagulation factors. Subsequently, we detected a factor V inhibitor and anti-factor V autoantibodies was confirmed using enzyme-linked immunosorbent assay with purified human plasma factor V. Thus, the patient was 'definitely diagnosed' with AiFVD in accordance with the diagnostic criteria enacted by the Japanese Ministry of Health, Labor, and Welfare. The bleeding tendency improved after initiating oral prednisolone 50 mg (1 mg/kg) followed by normalization of activated partial thromboplastin time and prothrombin time at the 34th day. After improving the coagulation system prolongation, the inhibitor and autoantibodies has been eradicated. Since it is suggested that drug-induced immune response can cause AiFVD, AiFVD should be considered in patients who undergo hemodialysis and develop failure of hemostasis and drug-induced eruption.

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Books 【 display / non-display

Other Papers 【 display / non-display

  • ベリムマブが有効であった全身性エリテマトーデスによる間質性肺炎の一例

    金城 武士, 石田 明夫, 藤田 次郎

    日本臨床免疫学会総会プログラム・抄録集 ( 日本臨床免疫学会 )  47回   130 - 130   2019.10

     

  • パルボウィルス感染に伴うSLE様病態と鑑別を要したループス腎炎の一例

    平良浩菜, 大城菜々子, 大嶺久美子, 砂川祥頌, 中村卓人, 金城孝典, 山里正演, 石田明夫, 古波蔵健太郎, 大屋祐輔

    日本腎臓学会誌 ( (一社)日本腎臓学会 )  61 ( 6 ) 897 - 897   2019.08

     

    J-GLOBAL

  • 巣状分節性糸球体硬化症を発症した高齢者に,LDLアフェレーシスを併用した1例

    砂川祥頌, 座間味亮, 大城菜々子, 大嶺久美子, 平良浩菜, 中村卓人, 金城興次郎, 金城孝典, 恒吉章治, 相澤直輝, 山里正演, 石田明夫, 古波蔵健太郎, 大屋祐輔

    日本透析医学会雑誌 ( (一社)日本透析医学会 )  52 ( Suppl.1 ) 630 - 630   2019.05

     

    J-GLOBAL

  • 非ネフローゼ性慢性腎臓病における腎内レニンアンジオテンシン系に関連する因子

    平良浩菜, 古波蔵健太郎, 宮城剛志, 大城菜々子, 大嶺久美子, 砂川祥頌, 中村卓人, 座間味亮, 金城孝典, 山里正演, 石田明夫, 大屋祐輔

    日本腎臓学会誌 ( (一社)日本腎臓学会 )  61 ( 3 ) 367 - 367   2019.05

     

    J-GLOBAL

  • 外来通院中高血圧患者におけるカリウム摂取状況の調査

    高橋 信之介, 仲程 舞衣, 中村 卓人, 石田 明夫, 山里 正演, 古波蔵 健太郎, 大屋 祐輔

    琉球医学会誌 ( 琉球医学会 )  37 ( 1-4 ) 132 - 132   2018.12

     

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Academic Awards 【 display / non-display

  • Accommodation Grant Award

    2016   26th Scientific Meeting of International Society of Hypertension (Hypertension Seoul 2016)  

  • Best Poster Presentation

    2015   European Society of Cardiology (ESC) Congress 2015