Details of a Researcher - Imai Hideyuki

Imai Hideyuki

写真a

Title	Professor
Researcher Number(JSPS Kakenhi)	10359987
Homepage URL	https://researchmap.jp/read0119238?lang=en

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Current Affiliation Organization 【 display / non-display 】

Concurrently University of the Ryukyus Graduate School of Engineering and Science Marine and Environmental Sciences Professor
Duty University of the Ryukyus Faculty of Science Chemistry, Biology and Marine Science Professor

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Graduate School 【 display / non-display 】

　

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1999.03

Tokai University Graduate School, Division of Marine Science and Technology Doctor's Course (second term) Completed

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Academic degree 【 display / non-display 】

Tokai University - Doctor of Fisheries Science

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External Career 【 display / non-display 】

1999.12

-

2002.03

Oversea Fishery Cooperative Foundation (OFCF)
2002.10

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2006.03

University of the Ryukyus, Faculty of Science, Department of Chemistry, Biology, and Marine Science, Ecology and Systematics, Assitant Professor
2006.04

-

2007.03

University of the Ryukyus, Faculty of Science, Department of Chemistry, Biology, and Marine Science, Ecology and Systematics, Associate Professor
2007.04

-

2023.03

University of the Ryukyus, Faculty of Science, Department of Chemistry, Biology, and Marine Science, Ecology and Systematics, Associate Professor
2007.04

-

2023.03

University of the Ryukyus, Faculty of Science, Department of Chemistry, Biology, and Marine Science, Ecology and Systematics, Associate Professor

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Affiliated academic organizations 【 display / non-display 】

　

　

　

The Japanese Society of Fish Genetics and Breeding Science
　

　

　

The Japanese Society of Fisheries Science
1900.04

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Now

Japanese Society for Aquaculture Research
2007.10

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Now

The Biological Society of Okinawa
2011.04

-

Now

The biogeographical Society of Japan

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Research Areas 【 display / non-display 】

Others / Others
Life Science / Biodiversity and systematics
Life Science / Aquatic bioproduction science
Environmental Science/Agriculture Science / Conservation of biological resources

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Acquisition of a qualification 【 display / non-display 】

Forklift Driving Skilled Person

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Thesis 【 display / non-display 】

ノコギリガザミ類３種と分子的変異，これを遺伝的標識とした種苗放流の研究

1999.03

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Published Papers 【 display / non-display 】

Significant changes in fauna of the land-locked freshwater shrimp genus Neocaridina (Decapoda: Atyidae) in Japan over the past 15 years due to introduction of invasive alien species

Nagai H, Imai H

Biogeography 26 2024.09 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)
Taxonomic assessment of Acetes indicus H. Milne Edwards, 1830 (Crustacea, decapoda, Sergestoidea) as revealed from molecular and morphological analyses: re-validation of A. spiniger Hansen, 1919 and designation of a new species

Hanamura, Y., Hardianto, E., Fukuchi, J., Imai, H., Siow, R., Kanak, M. K., Islam, M. R., Tsutsui, I. and Kassim, F. M.

Bulletin of the National Museum of Nature and Science Series A (Zoology) 50 ( 2 ) 49 - 68 2024.05 [ Peer Review Accepted ]

Type of publication: Research paper (bulletin of university, research institution)
Genetic structure of the commercially important Asian monsoon scallop, Amusium pleuronectes (Linnaeus 1758), across the Indonesian Archipelago

Hardianto Eko, Permata Diah, Imai Hideyuki

Marine Ecology 45 e12793 2024.01 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)
Molecular ecology of the Javanese ricefish, Oryzias javanicus (Bleeker): genetic divergence along the Indonesian Archipelago

Hardianto E.

Marine and Freshwater Research ( Marine and Freshwater Research ) 74 ( 15 ) accepted - 1323 2023.09 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)
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Pleiotropic Functions of Nitric Oxide Produced by Ascorbate for the Prevention and Mitigation of COVID-19: A Revaluation of Pauling's Vitamin C Therapy.

Yamasaki H, Imai H, Tanaka A, Otaki JM

Microorganisms ( Microorganisms ) 11 ( 2 ) 397 - 397 2023.02 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

　View Summary

Linus Pauling, who was awarded the Nobel Prize in Chemistry, suggested that a high dose of vitamin C (l-ascorbic acid) might work as a prevention or treatment for the common cold. Vitamin C therapy was tested in clinical trials, but clear evidence was not found at that time. Although Pauling’s proposal has been strongly criticized for a long time, vitamin C therapy has continued to be tested as a treatment for a variety of diseases, including coronavirus infectious disease 2019 (COVID-19). The pathogen of COVID-19, SARS-CoV-2, belongs to the β-coronavirus lineage, which includes human coronavirus, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). This review intends to shed new light on vitamin C antiviral activity that may prevent SARS-CoV-2 infection through the chemical production of nitric oxide (NO). NO is a gaseous free radical that is largely produced by the enzyme NO synthase (NOS) in cells. NO produced by upper epidermal cells contributes to the inactivation of viruses and bacteria contained in air or aerosols. In addition to enzymatic production, NO can be generated by the chemical reduction of inorganic nitrite (NO2−), an alternative mechanism for NO production in living organisms. Dietary vitamin C, largely contained in fruits and vegetables, can reduce the nitrite in saliva to produce NO in the oral cavity when chewing foods. In the stomach, salivary nitrite can also be reduced to NO by vitamin C secreted from the epidermal cells of the stomach. The strong acidic pH of gastric juice facilitates the chemical reduction of salivary nitrite to produce NO. Vitamin C contributes in multiple ways to the host innate immune system as a first-line defense mechanism against pathogens. Highlighting chemical NO production by vitamin C, we suggest that controversies on the therapeutic effects of vitamin C in previous clinical trials may partly be due to less appreciation of the pleiotropic functions of vitamin C as a universal bioreductant.
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