IWASAKI Hironori

写真a

Title

associate professor

Laboratory Address

1 Senbaru,Nishihara,Okinawa

Mail Address

E-mail address

Current Affiliation Organization 【 display / non-display

  • Concurrently   University of the Ryukyus   Graduate School of Agriculture   Associate Professor  

  • Duty   University of the Ryukyus   Tropical Biosphere Research Center   associate professor  

External Career 【 display / non-display

  • 2002.04
     
     

    - , University of the Ryukyus, Tropical Biosphere Research Center, Research Associate  

  • 2002.04
     
     

     

  • 2002.04
    -
    2016.05

    University of the Ryukyus, Tropical Biosphere Research Center, Research Associate  

  • 2016.06
     
     

    University of the Ryukyus, Tropical Biosphere Research Center, Associate Professor  

Research Interests 【 display / non-display

  • food combination

  • synergistic effect

  • phytochemical

  • natural products chemistry

  • Cell-based assay

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Research Areas 【 display / non-display

  • Life Science / Applied molecular and cellular biology

  • Life Science / Molecular biology

  • Life Science / Food sciences

  • Life Science / Cell biology

  • Life Science / Applied biochemistry

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Research Theme 【 display / non-display

  • Screening of Cancer Promotion Inhibiting Activity from Food Material

  • Tumor Selective Cytotoxicity and Functional Analysis of Medical Herb Extract

Thesis 【 display / non-display

  • 動脈硬化易発ウズラの遺伝子変異に関する研究

    2000.03

Published Papers 【 display / non-display

  • Dietary polysaccharides extract from Spirulina platensis: a natural alternative for enhancing broiler performance and antioxidation status

    Pootthachaya, P and Puangsap, W and Pintaphrom, N and Srikha, T and Sompong, U and Cherdthong, A and Yuangsoi, B and Tengjaroensakul, B and Hironori, I and Wongtangtintharn, S

    British Poultry Science ( TAYLOR & FRANCIS )    1 - 14   2026.01 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    1. The demand for natural alternatives to antibiotic growth promoters in poultry has led to growing interest in bioactive compounds, such as polysaccharides derived from algae. This study evaluated the effects of algae (Spirulina platensis)-derived polysaccharides (ADP) on growth performance, blood profiles, carcase characteristics, meat quality, amino acid composition and antioxidant status in broilers. 2. A total of 320, 1-d-old Ross 308 mixed-sex broilers were randomly allocated to one of the five dietary treatments; a control diet (0% ADP) and diets supplemented with 0.15%, 0.30%, 0.45% and 0.60% of ADP. Each treatment included four replicates containing 16 birds each. The feeding trial was conducted over 42 d and was divided into three phases, including starter (1–14 d), grower (15–28 d) and finisher (29–42 d). 3. Dietary inclusion of ADP at 0.30% significantly improved body weight gain and feed conversion ratio during the finisher (1.77 kg and 1.71, respectively) and overall (2.82 kg and 1.56, respectively) periods. There were no adverse effects observed on haematological, serum biochemistry or carcase characteristics. 4. Supplementation with 0.45–0.60% ADP reduced cooking loss to 34–40% and improved meat cohesiveness by about 5%. Its inclusion elevated the levels of key amino acids, such as threonine, histidine, isoleucine, arginine and glutamic acid in the breast muscle. Additionally, ADP linearly increased hepatic antioxidant enzyme activities, including total superoxide dismutase (317.60–337.12 U/mg protein), glutathione peroxidase (39.98–48.70 U/mg protein), catalase (7.09–7.71 U/mg protein) and decreased malondialdehyde concentrations (0.63–0.68 nmol/mg protein) demonstrating enhanced oxidative status. These improvements were attributed to the prebiotic and antioxidant properties of Spirulina-derived polysaccharides, which enhance nutrient utilisation, maintain gut integrity and strengthen redox balance. 5. This study provides preliminary evidence that polysaccharides derived from S. platensis, particularly at 0.30–0.45%, can be used as safe and effective feed additives in broiler diets. These compounds have the potential to enhance performance, oxidative stability and certain aspects of meat quality without adverse effects.

  • Exploring the advantages of<i> Lactobacillus</i> species from plants for future therapeutics and foods

    Wichiansri, S; Siripornadulsil, S; Iwasaki, H; Siripornadulsil, W

    BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY ( Biocatalysis and Agricultural Biotechnology )  71   2026.01 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • Metabolomic changes and enhanced digestibility with algae (Spirulina platensis) derived polysaccharides supplementation in broilers

    Padsakorn Pootthachaya, Sawitree Wongtangtintharn, Warin Puangsap, Nisakon Pintaphrom, Theeraphat Srikha, Anusorn Cherdthong, Bundit Yuangsoi, Bundit Tengjaroensakul, Iwasaki Hironori

    Algal research ( Elsevier )  90   104112   2025.08 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

     View Summary

    The objective of this study was to investigate the effects of algae (Spirulina platensis)-derived polysaccharides (ADPs) on performance, digestibility, intestinal histomorphology, digestive enzyme activities, and metabolomic profiles in broiler chickens. A total of 320 one-day-old Ross 308 mixed-sex broilers were randomly allocated to 5 dietary treatments comprising 0 (Control), 1500, 3000, 4500, and 6000 mg ADPs/kg in a completely randomized design. Each treatment included 4 replications, with 16 birds per replicate. The feeding trial lasted 42 days, encompassing starter (1–10 days), grower (11–24 days), and finisher (25–42 days) phases. The results demonstrated that dietary ADPs supplementation at 3000 mg/kg significantly enhanced (P < 0.05) body weight gain and improved feed conversion ratio during the overall period (1–42 days). In addition, supplementation with 1500–4500 mg/kg ADPs significantly improved (P < 0.05) in vitro crude protein digestibility (period 2) and apparent metabolizable energy (periods 2 and 3). Meanwhile, in vivo digestibility was also enhanced by ADPs supplementation, with significant improvements (P < 0.05) in dry matter (period 2) and crude protein (periods 2 and 3) digestibility. Histomorphological analysis revealed that ADPs supplementation at 1500–6000 mg/kg significantly increased (P < 0.05) villus height, villus width, villus height-to-crypt depth ratio, and villus surface area throughout the small intestine. Additionally, digestive enzyme activities, including amylase, lipase, and protease, were significantly elevated (P < 0.05) in broilers supplemented 3000–4500 mg/kg ADPs. Metabolomic analysis identified significant alterations in liver and breast muscle metabolites, with 194 differentially expressed metabolites in the liver and 134 in the breast, primarily associated with amino acid metabolism pathways. In the liver, the most affected pathways included lysine degradation, glycine-serine-threonine metabolism, and arginine biosynthesis. In the breast muscle, key pathways included phenylalanine-tyrosine-tryptophan biosynthesis, glycine-serine-threonine metabolism, and valine-leucine-isoleucine biosynthesis. Regarding principal component analysis demonstrated distinct clustering between control and ADPs-treated groups, indicating notable metabolic shifts. These findings suggest that the supplementation of ADPs from S. platensis enhances nutrient digestibility, intestinal morphology, digestive enzyme activity, and key metabolic pathways, ultimately supporting broiler growth performance. Based on the comprehensive findings of this study, dietary supplementation with ADPs at 3000 mg/kg is recommended as the optimal level.

  • Stress amelioration and anti-inflammatory potential of Shiikuwasha (Citrus depressa Hayata) essential oil, limonene, and γ-terpinene

    Y Asikin, K Shimizu, H Iwasaki, H Oku, K Wada

    Journal of Food and Drug Analysis ( Journal of Food and Drug Analysis )  30 ( 3 ) 454 - 465   2022.09 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

  • The dose-dependent pteryxin-mediated molecular mechanisms in suppressing adipogenesis in vitro

    Ruwani N Nugara, Hirosuke Oku, Seiko Saitoh, Masashi Inafuku, Hironori Iwasaki, RP Kumara, LJS Undugoda, BNS Lankasena

    Journal of Functional Foods ( Journal of Functional Foods )  82   2021.07 [ Peer Review Accepted ]

    Type of publication: Research paper (scientific journal)

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Other Papers 【 display / non-display

  • A study of synergistic anti-obesity effects of arctigenin and nobiletin.

    与儀彪, 岩崎公典, 屋宏典

    日本農芸化学会大会講演要旨集(Web)   2023   2023

     

    J-GLOBAL

  • Study on the synergistic anti-obesity effects induced by the combination of arctigenin and nobiletin

    与儀彪, 岩崎公典, 屋宏典

    日本農芸化学会大会講演要旨集(Web)   2022   2022

     

    J-GLOBAL

  • Study of the molecular mechanism of synergistic antitumor activity by Arctigenin and Nobiletin

    仲宗根侑花, 岩崎公典, 屋宏典

    日本農芸化学会大会講演要旨集(Web)   2021   2021

     

    J-GLOBAL

  • 沖縄県与那国町産ボタンボウフウ(長命草)の抗メタボリックシンドローム作用とその寄与成分

    稲福征志, 岩崎公典, 大野智, 坂上未紀, 屋宏典

    日本栄養・食糧学会大会講演要旨集   71st   167   2017.04

     

    J-GLOBAL

  • Camptothecin耐性癌細胞に対する植物アルカロイドNitidineの効果

    平良直幸, 岩崎公典, 稲福征志, 屋宏典

    日本栄養・食糧学会九州・沖縄支部大会講演要旨集   2015   81   2015.10

     

    J-GLOBAL

Presentations 【 display / non-display

  • Exploration of reward compounds provided by Alocasia odora inflorescences to its pollinators: two species of Colocasiomyia flies

    2026.03  -  2026.03 

  • Microbiome composition of the exudate within the infructescence of Alocasia odora (Araceae)

    2026.03  -  2026.03 

Grant-in-Aid for Scientific Research 【 display / non-display

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2020.04  -  2023.03 

    Direct: 13,800,000 (YEN)  Overheads: 17,940,000 (YEN)  Total: 4,140,000 (YEN)

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2020  -  2023 

    Direct: 0 (YEN)  Overheads: 0 (YEN)  Total: 0 (YEN)

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2011  -  2013 

    Direct: 0 (YEN)  Overheads: 0 (YEN)  Total: 0 (YEN)

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2008  -  2010 

    Direct: 3,200,000 (YEN)  Overheads: 960,000 (YEN)  Total: 4,160,000 (YEN)

Social Activity 【 display / non-display

  • 2025.10