研究者詳細 - 古泉　英貴

論文 - 古泉　英貴

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【自発蛍光で読み解く眼底疾患】加齢黄斑変性と眼底自発蛍光

今永直也, 古泉英貴

眼科グラフィック ( (株)メディカ出版 ) 8 ( 5 ) 547 - 559 2019年10月

掲載種別: 研究論文（その他学術会議資料等）

【いちばんやさしいOCTの撮りセツ】疾患別OCT画像の撮り方、見方まずはこれだけ3疾患加齢黄斑変性

冨山亜季子, 古泉英貴

眼科ケア ( (株)メディカ出版 ) 21 ( 10 ) 1016 - 1025 2019年10月

掲載種別: 研究論文（その他学術会議資料等）

高齢者糖尿病における糖尿病性網膜症の発症及び悪化要因に関する臨床疫学的後方視解析

新里幸子, 中山良朗, 比嘉盛丈, 新垣孝一郎, 島袋充生, 古泉英貴, 益崎裕章

糖尿病 ( (一社)日本糖尿病学会 ) 62 ( 9 ) 611 - 611 2019年09月

掲載種別: 研究論文（その他学術会議資料等）

原発開放隅角緑内障および高眼圧症に対するオミデネパグイソプロピルの短期成績

宮平大輝, 酒井寛, 大橋和広, 力石洋平, 新垣淑邦, 酒井美也子, 古泉英貴

日本緑内障学会抄録集 ( 日本緑内障学会 ) 30回 85 - 85 2019年09月

掲載種別: 研究論文（その他学術会議資料等）

Space gravitational-wave antennas DECIGO and B-DECIGO

Kawamura, S; Nakamura, T; Ando, M; Seto, N; Akutsu, T; Funaki, I; Ioka, K; Kanda, N; Kawano, I; Musha, M; Nakazawa, K; Sato, S; Takashima, T; Tanaka, T; Tsubono, K; Yokoyama, J; Agatsuma, K; Aoyanagi, K; Arai, K; Araya, A; Aritomi, N; Asada, H; Aso, Y; Chen, D; Chiba, T; Ebisuzaki, T; Eguchi, S; Ejiri, Y; Enoki, M; Eriguchi, Y; Fujimoto, MK; Fujita, R; Fukushima, M; Futamase, T; Gondo, R; Harada, T; Hashimoto, T; Hayama, K; Hikida, W; Himemoto, Y; Hirabayashi, H; Hiramatsu, T; Hong, FL; Horisawa, H; Hosokawa, M; Ichiki, K; Ikegami, T; Inoue, KT; Ishihara, H; Ishikawa, T; Ishizaki, H; Ito, H; Itoh, Y; Izumi, K; Kanemura, S; Kawashima, N; Kawazoe, F; Kishimoto, N; Kiuchi, K; Kobayashi, S; Kohri, K; Koizumi, H; Kojima, Y; Kokeyama, K; Kokuyama, W; Kotake, K; Kozai, Y; Kunimori, H; Kuninaka, H; Kuroda, K; Kuroyanagi, S; Maeda, K; Matsuhara, H; Matsumoto, N; Michimura, Y; Miyakawa, O; Miyamoto, U; Miyoki, S; Morimoto, MY; Morisawa, T; Moriwaki, S; Mukohyama, S; Nagano, S; Nakamura, K; Nakano, H; Nakao, K; Nakasuka, S; Nakayama, Y; Nishida, E; Nishizawa, A; Niwa, Y; Noumi, T; Obuchi, Y; Ohishi, N; Ohkawa, M; Okada, K; Okada, N; Okutomi, K; Oohara, K; Sago, N; Saijo, M; Saito, R; Sakagami, M; Sakai, S; Sakata, S; Sasaki, M; Sato, T; Shibata, M; Shibata, K; Shimo-oku, A; Shinkai, H; Shoda, A; Somiya, K; Sotani, H; Suemasa, A; Sugiyama, N; Suwa, Y; Suzuki, R; Tagoshi, H; Takahashi, F; Takahashi, K; Takahashi, K; Takahashi, R; Takahashi, R; Takahashi, H; Akiteru, T; Takano, T; Tanaka, N; Taniguchi, K; Taruya, A; Tashiro, H; Torii, Y; Toyoshima, M; Tsujikawa, S; Ueda, A; Ueda, K; Ushiba, T; Utashima, M; Wakabayashi, Y; Yagi, K; Yamamoto, K; Yamazaki, T; Yoo, CM; Yoshida, S; Yoshino, T

INTERNATIONAL JOURNAL OF MODERN PHYSICS D ( International Journal of Modern Physics D ) 28 ( 12 ) 2019年09月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Untitled Reply

Hasegawa, T; Kawano, T; Maruko, I; Koizumi, H; Iida, T

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES ( Retina ) 39 ( 6 ) E23 - E24 2019年06月 [ 査読有り ]

掲載種別: 研究論文（その他学術会議資料等）

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Untitled Reply

Hasegawa, T; Kawano, T; Maruko, I; Koizumi, H; Iida, T

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES ( Retina ) 39 ( 6 ) E25 - E25 2019年06月 [ 査読有り ]

掲載種別: 研究論文（その他学術会議資料等）

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加齢黄斑変性と脈絡膜の密なる関係

古泉英貴

日本眼科学会雑誌 ( (公財)日本眼科学会 ) 123 ( 4 ) 369 - 371 2019年04月

掲載種別: 研究論文（その他学術会議資料等）

【歪視の診断と治療】歪視と加齢黄斑変性

寺尾信宏, 古泉英貴

OCULISTA ( (株)全日本病院出版会 ) ( 71 ) 17 - 24 2019年02月

掲載種別: 研究論文（その他学術会議資料等）

【完全マスター加齢黄斑変性アップデート2019】長期経過を考えたポリープ状脈絡膜血管症治療抗VEGF薬単独療法

玉城環, 古泉英貴

あたらしい眼科 ( (株)メディカル葵出版 ) 36 ( 2 ) 181 - 189 2019年02月

掲載種別: 研究論文（その他学術会議資料等）

Pachychoroid disease

Cheung, CMG; Lee, WK; Koizumi, H; Dansingani, K; Lai, TYY; Freund, KB

EYE ( Eye Basingstoke ) 33 ( 1 ) 14 - 33 2019年01月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Pachychoroid is a relatively novel concept describing a phenotype characterized by attenuation of the choriocapillaris overlying dilated choroidal veins, and associated with progressive retinal pigment epithelium dysfunction and neovascularization. The emphasis in defining pachychoroid-related disorders has shifted away from simply an abnormally thick choroid (pachychoroid) toward a detailed morphological definition of a pathologic state (pachychoroid disease) with functional implications, which will be discussed in this review. Several clinical manifestations have been described to reside within the pachychoroid disease spectrum, including central serous chorioretinopathy, pachychoroid pigment epitheliopathy, pachychoroid neovasculopathy, polypoidal choroidal vasculopathy/aneurysmal type 1 neovascularization, focal choroidal excavation, peripapillary pachychoroid syndrome. These conditions all exhibit the characteristic choroidal alterations and are believed to represent different manifestations of a common pathogenic process. This review is based on both the current literature and the clinical experience of our individual authors, with an emphasis on the clinical and imaging features, management considerations, as well as current understanding of pathogenesis of these disorders within the context of the recent findings related to pachychoroid disease.

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Differences in Choroidal Structures Between Idiopathic and Steroid-Induced Central Serous Chorioretinopathy

Izumi T.

Journal of Vitreoretinal Diseases ( Journal of Vitreoretinal Diseases ) 3 ( 1 ) 10 - 15 2019年01月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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RESOLUTION OF FOVEAL CYST AFTER THE RELEASE OF VITREOMACULAR ATTACHMENT IN EYE WITH MACULAR TELANGIECTASIA TYPE 2.

Kimura M, Koizumi H, Maruko I, Iida T

Retinal cases & brief reports ( Retinal Cases and Brief Reports ) 13 ( 2 ) 118 - 120 2019年 [ 査読有り ]

掲載種別: 研究論文（その他学術会議資料等）

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CHOROIDAL BLOOD VESSELS IN RETINAL PIGMENT EPITHELIAL ATROPHY USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Maruko I, Koizumi H, Sawaguchi S, Hasegawa T, Arakawa H, Iida T

Retinal cases & brief reports ( Retinal Cases and Brief Reports ) 13 ( 1 ) 88 - 93 2019年 [ 査読有り ]

掲載種別: 研究論文（その他学術会議資料等）

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Anterior chamber paracentesis during intravitreal injections in observational trials: effectiveness and safety and effects.

Saxena S, Lai TY, Koizumi H, Farah ME, Ferrara D, Pelayes D, Sato T, Meyer CH, Murray T, International Pharmacokinetic Collaboration

International journal of retina and vitreous ( International Journal of Retina and Vitreous ) 5 ( 1 ) 8 - 8 2019年 [ 査読有り ]

掲載種別: 研究論文（その他学術会議資料等）

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Association of Upregulated Angiogenic Cytokines With Choroidal Abnormalities in Chronic Central Serous Chorioretinopathy

Terao, N; Koizumi, H; Kojima, K; Yamagishi, T; Nagata, K; Kitazawa, K; Yamamoto, Y; Yoshii, K; Hiraga, A; Toda, M; Kinoshita, S; Sotozono, C; Hamuro, J

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE ( Investigative Ophthalmology and Visual Science ) 59 ( 15 ) 5924 - 5931 2018年12月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Purpose: To clarify the distinct molecular pathogenesis of central serous chorioretinopathy (CSC) and pachychoroid neovasculopathy (PNV). Methods: Aqueous humor (AH) was collected from 18 acute CSC, 20 chronic CSC, and 20 PNV patients. Concentrations of 30 cytokines in the AH were analyzed using a multiplex bead immunoassay, and the cytokine profiles were compared among these three groups of patients. The areas of choroidal vascular hyperpermeability (CVH) and choroidal thickness (CT), including measurement of the vascular layers, were investigated to analyze the features of choroidal abnormality in acute CSC, chronic CSC, and PNV. Additionally, associations between cytokine profiles and choroidal abnormalities were analyzed. Results: Proinflammatory cytokines, IL-6 and IL-8 were significantly upregulated in the chronic CSC group compared with the acute CSC or PNV groups. Angiogenic cytokines and VEGF-A were upregulated at levels that almost reached significance along with disease progression from acute to chronic CSC, whereas the upregulation was not significant from chronic CSC to PNV. In the chronic CSC group, strong positive correlations were confirmed between VEGF-A and placental growth factor (PlGF) (r = 0.75, P < 0.001) and IL-6 and VEGF-A (r = 0.74, P < 0.001), and angiogenesis-related cytokines were positively correlated with the typical choroidal abnormalities, areas of CVH, mean CT, and mean large choroidal vessel layer thickness. However, there was no association between these choroidal abnormality parameters and AH cytokines in the PNV group. Conclusions: The results suggest that choroidal abnormalities in chronic CSC may be associated with upregulated angiogenesis.