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• Keyword analysis of the American Heart Association Basic Life Support Guidelines using a quantitative text analysis method

  SEKIGUCHI Hiroshi, NAKAMA Toshiharu, SATO Aya, MINEI Akira, KONDO Yutaka, FUKUDA Tatsuma, UENO Eiichi, UMEMURA Takehiro, KUKITA Ichiro

  Journal of Japanese Society for Emergency Medicine ( Japanese Society for Emergency Medicine )  27 ( 1 ) 40 - 47   2024.02 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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  <p><b>Background</b>: The American Heart Association (AHA) Basic Life Support (BLS) Healthcare Provider Manual was updated with new scientific evidence for resuscitation. The purpose of this study was to clarify the changes in keywords associated with guideline updates of the 2000, 2005, 2010, and 2015 AHA-BLS Healthcare Provider Manuals using a quantitative text analysis method.</p><p><b>Methods</b>: Using quantitative text analysis software (KH-coder), we analyzed the word frequency, co-occurrence network, and correspondence analysis of the AHA-BLS Japanese version of the Healthcare Provider Manual.</p><p><b>Results</b>: The top 20 extracted words were listed based on word frequency, and eight topics appeared in the co-occurrence network. Correspondence analysis extracted the following keywords: risk factors for cardiac arrest, foreign body airway obstruction, and heart massage in 2000, cardiac heart attack factors in 2005; assisted rescue breathing, agonal gasps, and CPR procedure in 2010; and team in 2015. The keyword common to all was CPR.</p><p><b>Conclusions</b>: Quantitative text analysis revealed keywords associated with the updates of the AHA-BLS guidelines in different years. </p>

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• Can Homecare Chronic Respiratory Disease Patients with Home Oxygen Treatment (HOT) in Southern Okinawa, Japan Be Evacuated Ahead of the Next Anticipated Tsunami?

  Hiroshi Sekiguchi, Rie Takeuchi, Yoko Sato, Tsuyoshi Matsumoto, Jun Kobayashi, Takehiro Umemura

  International Journal of Environmental Research and Public Health     2022.05 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• Survival From Pediatric Out-of-Hospital Cardiac Arrest During Nights and Weekends An Updated Japanese Registry-Based Study

  Tatsuma Fukuda, Naoko Ohashi-Fukuda, Hiroshi Sekiguchi, Ryota Inokuchi, Ichiro Kukita.

  JACC Asia     2022.04 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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• Association between time to advanced airway management and neurologically favourable survival during out-of-hospital cardiac arrest.

  Fukuda T, Ohashi-Fukuda N, Inokuchi R, Kondo Y, Sekiguchi H, Taira T, Kukita I

  Anaesthesia, critical care & pain medicine ( Anaesthesia Critical Care and Pain Medicine )  40 ( 4 ) 100906 - 100906   2021.08 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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  BACKGROUND: Advanced airway management (AAM) is commonly performed as part of advanced life support. However, there is controversy about the association between the timing of AAM and outcomes after out-of-hospital cardiac arrest (OHCA). This study aimed to determine whether time to AAM is associated with outcomes after OHCA. METHODS: This was a nationwide population-based observational study using the Japanese government-led registry of OHCA. Adults who experienced OHCA and received AAM by EMS personnel in the prehospital setting from 2014 to 2017 were included. Multivariable logistic regression models were used to assess the associations between time to AAM (defined as time in minutes from emergency call to the first successful AAM) and outcomes after OHCA. Then, associations between early (≤ 20 min) vs. delayed (> 20 min) AAM and outcomes after OHCA were examined using propensity score-matched analyses. The primary outcome was one-month neurologically favourable survival. RESULTS: A total of 164,223 patients (median [IQR] age, 80 [69-86] years; 57.7% male) were included. The median time to AAM was 17 min (IQR, 14-22). Longer time to AAM was significantly associated with a decreased chance of one-month neurologically favourable survival (multivariable adjusted OR per minute delay, 0.90 [95% CI, 0.90-0.91]). In the propensity score-matched cohort, compared with early AAM, delayed AAM was associated with a decreased chance of one-month neurologically favourable survival (516 of 50,997 [1.0%] vs. 226 of 50,997 [0.4%]; RR, 0.44; 95% CI, 0.37-0.51; NNT, 176). CONCLUSIONS: Delay in AAM was associated with a decreased chance of one-month neurologically favourable survival among patients with OHCA.

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• Epinephrine dosing interval and neurological outcome in out-of-hospital cardiac arrest.

  Fukuda T, Kaneshima H, Matsudaira A, Chinen T, Sekiguchi H, Ohashi-Fukuda N, Inokuchi R, Kukita I

  Perfusion ( Perfusion (United Kingdom) )    2676591211025163 - 026765912110251   2021.06 [ Peer Review Accepted ]

  Type of publication: Research paper (scientific journal)

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  <sec><title>Objective:</title> Current guidelines for cardiopulmonary resuscitation (CPR) recommend that standard-dose epinephrine be administered every 3–5 minutes during cardiac arrest. However, there is a knowledge gap regarding the optimal epinephrine dosing interval. This study aimed to examine the association between epinephrine dosing intervals and outcomes after out-of-hospital cardiac arrest (OHCA). </sec><sec><title>Methods:</title> This was a nationwide population-based observational study using data from a Japanese government-led registry of OHCA, including patients who experienced OHCA in Japan from 2011 to 2017. We defined the epinephrine dosing interval as the time interval between the first epinephrine administration and return of spontaneous circulation in the prehospital setting, divided by the total number of epinephrine doses. The primary outcome was 1-month neurologically favorable survival. </sec><sec><title>Results:</title> A total of 10,965 patients (mean (SD) age, 75.8 (14.3) years; 59.8% male) were included. The median epinephrine dosing interval was 3.5 minutes (IQR, 2.5–4.5; mean (SD), 3.6 (1.8)). Only approximately half of the patients received epinephrine administration with a standard dosing interval, as recommended in the current CPR guidelines. After multivariable adjustment, compared with the standard dosing interval, neither shorter nor longer epinephrine dosing intervals were associated with neurologically favorable survival after OHCA (Short vs Standard: adjusted OR 0.87 [95%CI 0.66–1.15]; and Long vs Standard: adjusted OR 1.08 [95%CI 0.76–1.55]). Similar associations were observed in propensity score-matched analyses. </sec><sec><title>Conclusions:</title> The epinephrine dosing interval was not associated with 1-month neurologically favorable survival after OHCA. Our findings do not deny the recommended epinephrine dosing interval in the current CPR guidelines. </sec>

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• Consideration of an Optimal Educational Strategy for High-Quality Cardiopulmonary Resuscitation and Chest Compression Fraction in Basic Life Support Simulation Training

  Hiroshi Sekiguchi, Ichiro Kukita

  The American Heart Association Scientific Sessions 2019  (Philadelphia, PA)  2019.11  -  2019.11 

• Verification on the possibility of evacuation of chronic respiratory disease patients in a Tsunami

  関口浩至

  The 47nd Annual Congress of The Society of Critical Care Medicine  (San Antonio, Texas, USA)  2018.02  -  2018.02 

• Verification of Changes in The Initiation Time for Chest Compressions using A Mannequin during Basic Life Support according to Modified Guidelines

  関口浩至、近藤豊、久木田一朗

  The 42nd Annual Congress of The Society of Critical Care Medicine  (San Juan, Puerto Rico, USA)  2013.02  -  2013.02 

• Verification on the possibility of evacuation of chronic respiratory disease patients in a Tsunami.

  Sekiguchi H, Kondo Y, Kukita I

  47th Annual Congress of the society of Critical Care Medicine（San Antonio, Texas, USA）  1900.01  -  1900.01 

• Consideration of an Optimal Educational Strategy for High-Quality Cardiopulmonary Resuscitation and Chest Compression Fraction in Basic Life Support Simulation Training

  関口 浩至

  American Hoeart Association Resuscitation Scientific Sessions 2019  1900.01  -  1900.01 

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• Grant-in-Aid for Scientific Research(B)

  Project Year: 2023.04  -  2026.03 

  Direct: 14,500,000 (YEN)  Overheads: 18,850,000 (YEN)  Total: 4,350,000 (YEN)

• Grant-in-Aid for Scientific Research(B)

  Project Year: 2023.04  -  2026.03 

  Direct: 14,500,000 (YEN)  Overheads: 18,850,000 (YEN)  Total: 4,350,000 (YEN)

• Grant-in-Aid for Young Scientists(A)

  Project Year: 2022.04  -  2025.03 

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• 2018.03

  　

  　

• 2016.07

  　

  　

• 2015.07

  　

  　

• 2008.11

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• 琉球大学地域連携推進機構 

  2018.3