Yanagi Teruki

写真a

Title

Associate Professor

Current Affiliation Organization 【 display / non-display 】

  • Duty   University of the Ryukyus   Graduate School of Medicine   Associate Professor  

Academic degree 【 display / non-display 】

  • Hokkaido University -  PhD

Affiliated academic organizations 【 display / non-display 】

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    THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY 

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    THE JAPANESE DERMATOLOGICAL ASSOCIATION 

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    THE JAPANESE CANCER ASSOCIATION 

Research Interests 【 display / non-display 】

  • 皮膚腫瘍学

Research Areas 【 display / non-display 】

  • Life Science / Tumor biology

  • Life Science / Dermatology

Published Papers 【 display / non-display 】

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Other Papers 【 display / non-display 】

  • CDK4/6 in extramammary Paget disease

    柳輝希

    臨床皮膚科   77 ( 5 ) 54 - 57   2023.04  [Refereed]

     

    J-GLOBAL

  • Two cases of basal cell nevus syndrome responded to imiquimod

    小川弘記, 北村真也, 田中有沙, 山賀三紗子, 平野瑶子, 瀬尾拓志, 葭本倫大, 加藤直子, 柳輝希, 氏家英之

    臨床皮膚科   77 ( 4 ) 347 - 352   2023.04  [Refereed]

     

    J-GLOBAL

  • Type 1 diabetes mellitus in a melanoma patient treated with adjuvant nivolumab therapy

    Takuya Maeda, Shinya Kitamura, Teruki Yanagi, Atsushi Narahira, Kodai Miyamoto, Hiroo Hata, kyu Yong Cho, Hiraku Kameda, Akinobu Nakamura, Hiroshi Shimizu

    Journal of Cutaneous Immunology and Allergy   2 ( 6 ) 176 - 177   2019.12  [Refereed]

     

    DOI Open Access

  • 扁平上皮癌におけるTripartite motif‐containing protein 29(TRIM29)の検討

    柳輝希, 秦洋郎, 北村真也, 清水宏, 柳紘子, 本間明宏, 渡部昌, 畠山鎮次

    日本皮膚科学会雑誌   129 ( 5 ) 1170 - 1170   2019.05

     

    J-GLOBAL

  • 扁平上皮におけるTripartite motif‐containing protein 29(TRIM29)の機能解析

    柳輝希, 秦洋郎, 北村真也, 今福恵輔, 清水宏, 柳紘子, 本間明宏, 渡部昌, 畠山鎮次

    日本皮膚科学会雑誌   129 ( 1 ) 45 - 45   2019.01

     

    DOI J-GLOBAL

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Grant-in-Aid for Scientific Research 【 display / non-display 】

  • Development of a novel therapeutic strategy for angiosarcoma through drug screening

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2023.04  -  2026.03 

    Direct: 3,600,000 (YEN)  Overheads: 4,680,000 (YEN)  Total: 1,080,000 (YEN)

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2022.04  -  2025.03 

    Direct: 3,300,000 (YEN)  Overheads: 4,290,000 (YEN)  Total: 990,000 (YEN)

  • Grant-in-Aid for Scientific Research(B)

    Project Year: 2021.04  -  2024.03 

    Direct: 13,300,000 (YEN)  Overheads: 17,290,000 (YEN)  Total: 3,990,000 (YEN)

  • Genome-wide screening of the key molecules for metastasizing collagen VII-deficient squamous cell carcinoma.

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2019.04  -  2022.03 

    Direct: 3,300,000 (YEN)  Overheads: 4,290,000 (YEN)  Total: 990,000 (YEN)

  • Genome-wide screening of the key molecules for metastasizing collagen VII-deficient squamous cell carcinoma.

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2019.04  -  2022.03 

    Investigator(s): Nakamura Hideki 

    Direct: 3,300,000 (YEN)  Overheads: 4,290,000 (YEN)  Total: 990,000 (YEN)

     View Summary

    The aim of this study was to elucidate the metastatic mechanism of squamous cell carcinoma (SCC) arising in patients with dystrophic epidermolysis bullosa (DEB) caused by mutations in type 7 collagen (COL7) gene. DEB patient model keratinocytes with a comprehensive gene-editing did not develop metastasis when transplanted subcutaneously in mice, but the subcutaneous tumors of DEB patient model showed an overall irregular structure, surrounding fibrosis, and hypervascularization compared to subcutaneous tumors of normal keratinocytes. These results suggest that subcutaneous tumors in DEB patient model induce changes in the surrounding tissue environment via abnormal construction of the basement membrane, and that these changes may contribute to the metastatic mechanism of SCC in DEB patients.

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