論文 - 荒川　雅志

The Smart Life Stay (SLS) program: effects of a lifestyle intervention program in combination with health tourism and health guidance for type 2 diabetes.

Madoka Matsushita, Akiko Muramoto, Eri Nomura, Yukari Eguchi, Ayako Kato, Yoshiko Sano, Mai Kabayama, Masashi Arakawa, Yuko Oguma, Daisuke Yabe, Masaaki Matsunaga, Hiroshi Yatsuya, Hiroshi Arima, Kazuyo Tsushita

Nutrition & diabetes   10 ( 1 ) 33 - 33   2020年08月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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BACKGROUND: The aim of this study was to determine the effectiveness of the Smart Life Stay (SLS) program, which is an experience-oriented stayover program, in combination with health tourism and mandatory health guidance on glucose metabolism after 2 years. METHODS: The participants of the SLS program (n = 792) were recruited from a database of 23 medical insurers. They underwent a mandatory health examination termed Specific Health Checkups in 2014. The participants were included if they had diabetes or were at a high risk of diabetes and if they satisfied the following inclusion criteria: (1) body mass index (BMI; kg/m2) > 25, or (2) waist circumference (WC; cm) > 85 for men and > 90 for women, or (3) hemoglobin A1c (HbA1c; %) > 5.6, or (4) fasting plasma glucose (FPG; mg/dl) > 100. Individuals who corresponded to one or more items were included as study participants. The control subjects (n = 3645) were nonparticipants of the program who were selected from the database and met the inclusion criteria. The lifestyle changes and changes in mean BMI, WC, FPG, and HbA1c in both groups from baseline to 2-year follow-up were compared by inverse probability weighting of a propensity score. RESULTS: The percentage of people who exercised regularly increased significantly in the SLS group compared with the control group. In the SLS group, BW, BMI, and WC significantly decreased by 1.75 kg, 0.60 kg/m2, and 1.45 cm, respectively, whereas in the control group, WC, FPG, and HbA1c increased significantly by 0.38 cm, 3.37 mg/dl, and 0.12%, respectively. The comparison between groups revealed that the BW, BMI, WC, FPG, and HbA1c improved significantly in the SLS group. CONCLUSIONS: The SLS program is suggested to help improve glucose metabolism. This program could be a feasible option as a lifestyle intervention program for diabetes.

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BAIAP2 rs8079781, postnatal smoking exposure, and emotional problems in Japanese children aged 5 years: the Kyushu Okinawa Maternal and Child Health Study

Yoshihiro Miyake, Keiko Tanaka, Masashi Arakawa

Journal of Neural Transmission ( Springer Science and Business Media LLC )  127 ( 7 ) 1081 - 1087   2020年07月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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地域資源をヘルスケア資源へ～宿泊型新保健指導の実際～

荒川雅志

Precision Medicine   3 ( 3 ) 96 - 100   2020年03月

掲載種別: 研究論文（学術雑誌）

Maternal consumption of vegetables, fruit, and antioxidants during pregnancy and risk for childhood behavioral problems

Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Masashi Arakawa

Nutrition ( Elsevier BV )  69   110572 - 110572   2020年01月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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旅の力を活かした新たな健康増進,ウェルネス健康経営プログラムの開発 : ウェルネスツーリズム・ウェルネスサードプレイスの実際

荒川 雅志

Precision medicine   3(10)   905 - 910   2020年

掲載種別: 研究論文（学術雑誌）

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地域資源をヘルスケア資源へ～宿泊型新保健指導の実際～

荒川 雅志

Precision Medicine   3   96 - 100   2020年

掲載種別: 研究論文（学術雑誌）

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Calcium intake during pregnancy is associated with decreased risk of emotional and hyperactivity problems in five-year-old Japanese children.

Takahashi K, Tanaka K, Nakamura Y, Okubo H, Sasaki S, Arakawa M, Miyake Y

Nutritional neuroscience     1 - 8   2019年11月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Maternal caffeine intake in pregnancy is inversely related to childhood peer problems in Japan: The Kyushu Okinawa Maternal and Child Health Study.

Miyake Y, Tanaka K, Okubo H, Sasaki S, Arakawa M

Nutritional neuroscience   22 ( 11 ) 817 - 824   2019年11月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Electronic and Geometric Effects on Chemical Reactivity of 3d-Transition-Metal-Doped Silver Cluster Cations toward Oxygen Molecules

Shun Sarugaku, Masashi Arakawa, Tomoki Kawano, Akira Terasaki

The Journal of Physical Chemistry C ( American Chemical Society (ACS) )  123 ( 42 ) 25890 - 25897   2019年09月

掲載種別: 研究論文（学術雑誌）

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Preterm birth is associated with higher prevalence of wheeze and asthma in a selected population of Japanese children aged three years

N. Takata, K. Tanaka, C. Nagata, M. Arakawa, Y. Miyake

Allergologia et Immunopathologia ( Elsevier BV )  47 ( 5 ) 425 - 430   2019年09月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Adsorption Kinetics of Nitrogen Molecules on Size-Selected Silver Cluster Cations

Tomonori Ito, Masashi Arakawa, Yuki Taniguchi, Akira Terasaki

Zeitschrift für Physikalische Chemie ( Walter de Gruyter GmbH )  233 ( 6 ) 759 - 770   2019年04月

掲載種別: 研究論文（学術雑誌）

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<jats:title>Abstract</jats:title> <jats:p>We present adsorption processes of dinitrogen on size-selected silver cluster cations, Ag<jats:sub> <jats:italic>n</jats:italic> </jats:sub> <jats:sup>+</jats:sup> (<jats:italic>n</jats:italic> = 1–10), studied by kinetics measurement using an ion trap. The cluster ions showed sequential adsorption of N<jats:sub>2</jats:sub> molecules when the ion trap was cooled down to 105 K, excluding <jats:italic>n</jats:italic> = 8 and 9 that were exceptionally inactive at this temperature. Termolecular rate coefficients of each adsorption step are determined by analyzing time-dependent changes in the reactant and product ion signals. The first-step rate coefficients were found to increase exponentially from <jats:italic>n</jats:italic> = 1 to 7 due to increased internal degrees of freedom at larger sizes, which are favorable for accommodating the adsorption energy in a free cluster. In contrast, the adsorption rate turned to decrease for <jats:italic>n</jats:italic> > 7 due to weaker binding of dinitrogen as revealed by density-functional-theory (DFT) calculation. Adsorption sites on Ag<jats:sub> <jats:italic>n</jats:italic> </jats:sub> <jats:sup>+</jats:sup> are further discussed on the basis of the maximum number of adsorbing N<jats:sub>2</jats:sub> molecules observed in the experiment.</jats:p>

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Charge-state analysis of small barium-oxide clusters by x-ray absorption spectroscopy.

Hayakawa T, Arakawa M, Ando K, Kiyomura Y, Kawano T, Terasaki A

Journal of physics. Condensed matter : an Institute of Physics journal   31 ( 13 ) 134003   2019年04月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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ウェルネス、ウェルネスツーリズムと沖縄

荒川 雅志

南方資源利用技術研究会誌 = Journal of the Society of Tropical Resources Technologists ( 南方資源利用技術研究会 )  34 ( 1 ) 1 - 6   2019年03月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

運動によるState-Trait Anxiety Inventory得点及びCenter for Epidemiologic Studies Depression Scale得点への影響 無作為化比較試験

本村 純, 荒川 雅志, 與古田 孝夫, 粟田 久多佳

琉球医学会誌 ( 琉球医学会 )  38 ( 1-4 ) 35 - 45   2019年 [ 査読有り ]

掲載種別: 研究論文（その他学術会議資料等）

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メタボリックシンドローム(MetS)またはMetS予備群の30歳代から50歳代の沖縄県民45名を対象に、同一の運動強度の海水運動と陸上運動が与えるState-Trait Anxiety Inventory(STAI)及びCenter for Epidemiologic Studeis Depression Scale(CES-D)得点への影響について検討した。対象は海水プールでの運動群、陸上運動群、運動を行わない非運動群(各15名)に分け、10週間の介入試験を行った。検討内容は介入前後のBMI、STAI状態不安得点、STAI特性不安得点、CES-D得点の変化とした。その結果、有意差を認めたのは、BMIで陸上群と非運動群間、STAI状態不安得点の変化率で海水群と非運動群間、陸上群と非運動群間であった。

ITIH3 and ITIH4 polymorphisms and depressive symptoms during pregnancy in Japan: the Kyushu Okinawa Maternal and Child Health Study.

Miyake Y, Tanaka K, Arakawa M

Journal of neural transmission (Vienna, Austria : 1996)   125 ( 10 ) 1503 - 1509   2018年10月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Maternal fat intake during pregnancy and behavioral problems in 5-y-old Japanese children

Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Masashi Arakawa

Nutrition ( Elsevier Inc. )  50   91 - 96   2018年06月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Objective: The aim of this cohort study was to investigate the relationship between maternal fat consumption during pregnancy and behavioral problems in 1199 Japanese children at age 5 y. Methods: Dietary intake of mothers during pregnancy was assessed using a diet history questionnaire. Emotional, conduct, hyperactivity, and peer problems in children were assessed using the Strengths and Difficulties Questionnaire the four scale scores were dichotomized, comparing children with borderline and abnormal scores to children with normal scores. Logistic regression analysis was applied to estimate adjusted odds ratios and 95% confidence intervals for each behavioral problem according to the quartile of dietary factors under study, adjusting for potential confounding factors. Results: Higher maternal intake of monounsaturated fatty acids, α-linolenic acid, ω-6 polyunsaturated fatty acids, and linoleic acid during pregnancy was independently associated with an increased risk for childhood emotional problems. The adjusted odds ratios between extreme quartiles (95% confidence intervals, Ptrend) were 1.85 (1.11 − 3.17, 0.04), 1.60 (0.99 − 2.60, 0.03), 2.06 (1.24 − 3.46, 0.002), and 2.09 (1.26 − 3.51, 0.002), respectively. No such positive associations were observed for the other outcomes. No relationships were found between maternal intake of total fat, saturated fatty acids, ω-3 polyunsaturated fatty acids, eicosapentaenoic acid, docosahexaenoic acid, arachidonic acid, or cholesterol, or the ratio of ω-3 to ω-6 polyunsaturated fatty acid intake during pregnancy and any of the outcomes. Conclusions: Maternal consumption of monounsaturated fatty acids, α-linolenic acid, ω-6 polyunsaturated fatty acids, and linoleic acid during pregnancy may increase the risk for childhood emotional problems.

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Breastfeeding duration is inversely associated with asthma in Japanese children aged 3 years.

Watanabe JI, Tanaka K, Nagata C, Furukawa S, Arakawa M, Miyake Y

The Journal of asthma : official journal of the Association for the Care of Asthma   55 ( 5 ) 511 - 516   2018年05月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Soy isoflavone intake and prevalence of depressive symptoms during pregnancy in Japan: baseline data from the Kyushu Okinawa Maternal and Child Health Study

Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Shinya Furukawa, Masashi Arakawa

European Journal of Nutrition ( Dr. Dietrich Steinkopff Verlag GmbH and Co. KG )  57 ( 2 ) 441 - 450   2018年03月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Objective: Several observational studies and trials examined the relationship between isoflavones or soybeans and depressive symptoms among peri- and postmenopausal women. We cross-sectionally evaluated the associations between intake of soy products and isoflavones and depressive symptoms during pregnancy in Japan. Methods: Study subjects were 1745 pregnant women. Dietary intake during the preceding month was assessed using a self-administered diet history questionnaire. Depressive symptoms were defined by a score of 16 or over in the Center for Epidemiologic Studies Depression Scale. Results: Higher intake of total soy products, tofu, tofu products, fermented soybeans, boiled soybeans, miso soup, and isoflavones was independently related to a lower prevalence of depressive symptoms during pregnancy: The adjusted prevalence ratios (95 % confidence intervals, P for trend) between extreme quartiles were 0.63 (0.47–0.85, 0.002), 0.72 (0.54–0.96, 0.007), 0.74 (0.56–0.98, 0.04), 0.57 (0.42–0.76, OpenSPiltSPi0.0001), 0.73 (0.55–0.98, 0.03), 0.65 (0.49–0.87, 0.003), and 0.63 (0.46–0.86, 0.002), respectively. A significant positive exposure–response relationship was found between miso intake and depressive symptoms during pregnancy. No material relationship was observed between soymilk intake and depressive symptoms during pregnancy. Conclusions: Our study is the first to show independent inverse relationships between intake of total soy products, tofu, tofu products, fermented soybeans, boiled soybeans, miso soup, and isoflavones and depressive symptoms during pregnancy.

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Dietary patterns and depressive symptoms during pregnancy in Japan: Baseline data from the Kyushu Okinawa Maternal and Child Health Study

Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Shinya Furukawa, Masashi Arakawa

JOURNAL OF AFFECTIVE DISORDERS ( ELSEVIER SCIENCE BV )  225   552 - 558   2018年01月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Background: Only one Brazilian study has examined the association between dietary patterns and depressive symptoms during pregnancy. The current cross-sectional study examined this issue in Japan. Methods: Study subjects were 1744 pregnant women. Between April 2007 and March 2008, information under study was obtained. Dietary patterns were derived from a factor analysis of 33 predefined food groups based on a self-administered diet history questionnaire. Depressive symptoms were defined as a Center for Epidemiological Studies Depression Scale score &gt;= 16. Adjustment was made for age, gestation, region of residence, number of children, family structure, history of depression, family history of depression, smoking, secondhand smoke exposure, employment, household income, education, and body mass index. Results: Three dietary patterns were identified: 'healthy', characterized by high intake of green and yellow vegetables, other vegetables, mushrooms, pulses, seaweed, potatoes, fish, sea products, miso soup, sugar, and shellfish; 'Japanese', characterized by high intake of rice and miso soup; and 'Western', characterized by high intake of beef and pork, processed meat, vegetable oil, chicken, eggs, shellfish, and salt-containing seasonings. The healthy and Japanese patterns were independently inversely associated with depressive symptoms during pregnancy: the adjusted prevalence ratios (95% confidence intervals, P for trend) between extreme quartiles were 0.56 (0.43-0.73,&lt; 0.0001) and 0.72 (0.55-0.94, 0.008), respectively. No association was observed between the Western pattern and depressive symptoms during pregnancy. Limitations: Information was obtained between the 5th and 39th week of pregnancy. Conclusions: The healthy and Japanese dietary patterns may be inversely associated with depressive symptoms during pregnancy.

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Parental occupations, educational levels, and income and prevalence of dental caries in 3-year-old Japanese children

Hiromasa Kato, Keiko Tanaka, Ken Shimizu, Chisato Nagata, Shinya Furukawa, Masashi Arakawa, Yoshihiro Miyake

Environmental Health and Preventive Medicine ( BioMed Central Ltd. )  22 ( 1 ) 80   2017年12月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

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Background: Most studies have investigated the association between parental socioeconomic factors and dental caries in children based on educational and income levels studies focusing on parental occupation, however, have been relatively limited. This cross-sectional study examined the associations between parental occupations and levels of education and household income and the prevalence of dental caries in Japanese children aged 3 years. Methods: Study subjects were 6315 children. Oral examination results were obtained from the parents or guardians, who transcribed the information recorded by medical staff at a public health center from their maternal and child health handbooks to our self-administered questionnaire. Children were classified as having dental caries if one or more primary teeth had decayed or had been filled. Adjustment was made for sex, age, region of residence, breastfeeding duration, between-meal snack frequency, toothbrushing frequency, use of fluoride, regular dental check-ups, maternal smoking during pregnancy, and living with at least one household smoker. Results: The prevalence of dental caries was 14.7%. Compared with having an unemployed father, having a father employed in professional and engineering, clerical, sales, security, or manufacturing process was significantly associated with a lower prevalence of dental caries. Compared with having an unemployed mother, having a mother employed in professional and engineering or service was significantly inversely associated with the prevalence of dental caries. Significant inverse associations were observed between parental levels of education and household income and the prevalence of dental caries. Conclusions: The findings of our study suggest that parental occupation affects the prevalence of dental caries in children. We confirm that higher levels of parental education and household income decreased the prevalence of dental caries.

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