研究者詳細 - 荒川　雅志

論文 - 荒川　雅志

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Sibling number and prevalence of allergic disorders in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study

Yoshihiro Miyake, Keiko Tanaka, Masashi Arakawa

BMC PUBLIC HEALTH ( BIOMED CENTRAL LTD ) 11 ( 561 ) 2011年07月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Background: Although an inverse relationship between number of siblings and likelihood of allergic disorders has been shown in many epidemiological studies, the biological mechanism underlying this phenomenon has not yet been identified. There is no epidemiological research regarding the sibling effect on allergic disorders in Japanese adults. The current cross-sectional study examined the relationship between number of siblings and prevalence of allergic disorders among adult women in Japan. Methods: Subjects were 1745 pregnant women. This study was based on questionnaire data. The definitions of wheeze and asthma were based on criteria from the European Community Respiratory Health Survey whereas those of eczema and rhinoconjunctivitis were based on criteria from the International Study of Asthma and Allergies in Childhood. Adjustment was made for age, region of residence, pack-years of smoking, secondhand smoke exposure at home and at work, family history of asthma, atopic eczema, and allergic rhinitis, household income, and education. Results: The prevalence values of wheeze, asthma, eczema, and rhinoconjunctivitis in the past 12 months were 10.4%, 5.5%, 13.0%, and 25.9%, respectively. A significant inverse exposure-response relationship was observed between the number of older siblings and rhinoconjunctivitis, but not wheeze, asthma, or eczema (P for trend = 0.03); however, the adjusted odds ratio (OR) for having 2 or more older siblings was not significant although the adjusted OR for having 1 older sibling was statistically significant (adjusted OR = 0.71 [95% CI: 0.56-0.91]). Number of total siblings and number of younger siblings were not related to wheeze, asthma, eczema, or rhinoconjunctivitis. Conclusions: This study found a significant inverse relationship between the number of older siblings and the prevalence of rhinoconjunctivitis among pregnant Japanese women. Our findings are likely to support the intrauterine programming hypothesis; however, we could not rule out the hygiene hypothesis.

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DOI 学術リポジトリ

Polyunsaturated fatty acid intake and prevalence of eczema and rhinoconjunctivitis in Japanese children: The Ryukyus Child Health Study

Yoshihiro Miyake, Keiko Tanaka, Satoshi Sasaki, Masashi Arakawa

BMC PUBLIC HEALTH ( BIOMED CENTRAL LTD ) 11 ( 358 ) 2011年05月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Background: The recent increase in the prevalence of allergic disorders might be a consequence of increased intake of n-6 polyunsaturated fatty acids (PUFAs) and reduced intake of n-3 PUFAs. The current cross-sectional study examined the association between intake levels and the prevalence of eczema and rhinoconjunctivitis in Japanese children. Methods: Subjects were 23,388 schoolchildren aged 6-15 years residing in Okinawa. The presence of eczema and/or rhinoconjunctivitis was determined according to the criteria of the International Study of Asthma and Allergies in Childhood. A brief diet history questionnaire for children and adolescents was administered to acquire information on dietary factors. Adjustment was made for age, sex, residential municipality, number of siblings, smoking in the household, body mass index, paternal and maternal history of allergic diseases, and paternal and maternal educational level. Results: The prevalences of eczema and rhinoconjunctivitis in the previous 12 months were 7.0% and 8.0%, respectively. Consumption of PUFAs, n-3 PUFAs, alpha-linolenic acid, n-6 PUFAs, and linoleic acid was positively associated with the prevalence of eczema: the adjusted odds ratios (ORs) between extreme quintiles (95% confidence intervals [CIs], P for trend) were 1.26 (1.07-1.48, 0.04), 1.31 (1.11-1.54, 0.009), 1.31 (1.12-1.55, 0.003), 1.26 (1.07-1.48, 0.01), and 1.27 (1.08-1.49, 0.01), respectively. Arachidonic acid intake was independently inversely related to eczema: the adjusted OR between extreme quintiles was 0.81 (0.69-0.95, 0.0008). Eczema was not associated with eicosapentaenoic or docosahexaenoic acid intake, or with the ratio of n-3 to n-6 PUFA intake. Only arachidonic acid intake was statistically significantly related to the prevalence of rhinoconjunctivitis, showing a clear inverse linear trend: the adjusted OR between extreme quintiles was 0.86 (0.74-0.997, 0.03). Conclusions: Consumption of n-3 and n-6 PUFAs, especially alpha-linolenic acid and linoleic acid, may be positively associated with eczema. Arachidonic acid intake may be inversely related to eczema and rhinoconjunctivitis.

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DOI 学術リポジトリ

Dietary Folate, Riboflavin, Vitamin B-6, and Vitamin B-12 and Depressive Symptoms in Early Adolescence: The Ryukyus Child Health Study

Kentaro Murakami, Yoshihiro Miyake, Satoshi Sasaki, Keiko Tanaka, Masashi Arakawa

PSYCHOSOMATIC MEDICINE ( LIPPINCOTT WILLIAMS & WILKINS ) 72 ( 8 ) 763 - 768 2010年10月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Objective: To examine the association between dietary folate, riboflavin, vitamin B-6, and vitamin B-12 and depressive symptoms in a group of adolescents. Methods: This cross-sectional study, conducted in all public junior high schools in Naha City and Nago City, Okinawa, Japan, included 3,067 boys and 3,450 girls aged 12 years to 15 years (52.3% of eligible sample). Dietary intake was assessed using a validated, self-administered diet history questionnaire. Depressive symptoms were defined as present when participants had a Center for Epidemiologic Studies Depression Scale score of >= 16. Results: The prevalence of depressive symptoms was 22.5% for boys and 31.2% for girls. Folate intake was inversely associated with depressive symptoms in both boys (adjusted odds ratio (OR) [95% confidence interval (CI)] in the highest (compared with the lowest) quintile, 0.60 [0.45, 0.79]; p for trend = .002) and girls (OR [95% CI], 0.61 [0.48, 0.77]; p for trend = <.001). Vitamin B-6 intake was inversely associated with depressive symptoms in both boys (OR [95% Cl], 0.73 [0.54, 0.98]; p for trend = .02) and girls (OR [95% Cl], 0.72 [0.56, 0.92]; p for trend = .002). Riboflavin intake was inversely associated with depressive symptoms in girls (OR [95% Cl], 0.85 [0.67, 1.08]; p for trend = .03), but not in boys. No clear association was seen between vitamin B-12 intake and depressive symptoms in either sex. Conclusions: This study suggests that higher intake of dietary B vitamins, particularly folate and vitamin B-6, is independently associated with a lower prevalence of depressive symptoms in early adolescence.

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Fish and n-3 Polyunsaturated Fatty Acid Intake and Depressive Symptoms: Ryukyus Child Health Study

Kentaro Murakami, Yoshihiro Miyake, Satoshi Sasaki, Keiko Tanaka, Masashi Arakawa

PEDIATRICS ( AMER ACAD PEDIATRICS ) 126 ( 3 ) E623 - E630 2010年09月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

BACKGROUND: Epidemiologic evidence on the role of fish and long-chain n-3 polyunsaturated fatty acid intake on depression during adolescence is sparse. OBJECTIVE: We examined the association between fish, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) intake and depressive symptoms in a group of adolescents. SUBJECTS AND METHOD: This cross-sectional study, conducted in all public junior high schools in Naha City and Nago City, Okinawa, Japan, included 3067 boys and 3450 girls aged 12 to 15 years (52.3% of the eligible sample). Dietary intake was assessed by using a validated, self-administered diet-history questionnaire. Depressive symptoms were defined as present when participants had a Center for Epidemiologic Studies Depression scale score of >= 16. RESULTS: The prevalence of depressive symptoms was 22.5% for boys and 31.2% for girls. For boys, fish intake was inversely associated with depressive symptoms (adjusted odds ratio [OR] for depressive symptoms in the highest [compared with the lowest] quintile of intake: 0.73 [95% confidence interval (CI): 0.55-0.97]; P for trend = .04). EPA intake showed an inverse association with depressive symptoms (OR: 0.71 [95% CI: 0.54-0.94]; P = .04). DHA intake also showed a similar inverse, albeit nonsignificant, association (OR: 0.79 [95% CI: 0.59-1.05]; P = .11). In addition, intake of EPA plus DHA was inversely associated with depressive symptoms (OR: 0.72 [95% CI: 0.55-0.96]; P = .08). Conversely, no such associations were observed among girls. CONCLUSIONS: Higher intake of fish, EPA, and DHA was independently associated with a lower prevalence of depressive symptoms in early male, but not female, adolescents. Pediatrics 2010;126:e623-e630

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Household smoking and dental caries in schoolchildren: the Ryukyus Child Health Study

Keiko Tanaka, Yoshihiro Miyake, Masashi Arakawa, Satoshi Sasaki, Yukihiro Ohya

BMC PUBLIC HEALTH ( BIOMED CENTRAL LTD ) 10 ( 10 ) 335 - 344 2010年06月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Background: Secondhand smoke exposure (SHSe) is perhaps one of the most important toxic exposures in childhood. However, epidemiological studies on the relation between SHSe and dental caries are limited and have yielded inconsistent results. The present cross-sectional study examined the potential association between SHSe at home and the prevalence of dental caries in children. Methods: Subjects were 20,703 schoolchildren aged 6 to 15 years in Okinawa, Japan. Information on SHSe at home and potential confounding factors was obtained through questionnaires. Data on dental caries were obtained from school records. Children were classified as having decayed and/or filled teeth (DFT) if a dentist diagnosed these conditions. Additionally, we analyzed decayed teeth (DT) and filled teeth (FT) separately. Adjustment was made for sex, age, region of residence, toothbrushing frequency, use of fluoride, sugar intake, and paternal and maternal educational level. Results: The prevalence of DFT was 82.0%. Compared with never smoking in the household, former and current household smoking were independently associated with an increased prevalence of DFT (adjusted prevalence ratios [95% confidence intervals] for former household smoking and current light and heavy household smoking were 1.03 [1.00-1.05], 1.04 [1.02-1.05], and 1.04 [1.03-1.06], respectively); when analyzed separately there was an increased prevalence of DT (adjusted prevalence ratios [95% confidence intervals] for former household smoking and current light and heavy household smoking were 1.06 [1.02-1.11], 1.10 [1.06-1.13], and 1.10 [1.07-1.14], respectively) but not FT. A statistically significant dose-response relationship between cumulative smoking in the household and the prevalence of DFT and DT (P for trend < 0.0001), but not FT, was observed. In an analysis of 2 subgroups, subjects who had at least 1 deciduous tooth and subjects who had at least 1 permanent tooth, household smoking exposure was associated with an increased prevalence of DFT and DT not only in those with deciduous but also those with permanent dentition. Conclusion: Our findings suggested that household smoking might be associated with an increased prevalence of dental caries in children.

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DOI 学術リポジトリ

スパセラピーのエビデンス－ヘルスツーリズム振興に向けた学術基盤整備－

荒川雅志, Arakawa Masashi

琉球大学観光科学 = Journal of tourism sciences, University of the Ryukyus ( 琉球大学観光産業科学部観光科学科 ) 2 ( 2 ) 47 - 62 2010年03月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Spa therapy is one of the most commonly used non-pharmacological approaches for health or medical tourism, but its health effects are not completely known. From the point of view in construction of knowledge in the field of health tourism, author constructed the evidence-table of spa therapy. The procedure of selection of the spa therapy is as follows; excluded "Not humans" (n=445), "Not English or Japanese" (n=456), "Not Randomized Controlled Trial" (n=897), "Not spa therapy or balneotherapy" (n=61). Finally, 41 interventional studies were extracted from approximately 20 million papers. Furthermore, we conducted spa intervention study in Okinawa. The participants (22 women, 42.6 +/- 8.2 years) were randomly assigned into two groups, an intervention group receiving spa therapy tour in Okinawa, and a control group carrying out normal daily life in study period. This study observed a significant improvement of evaluated sleep parameters at the end of spa therapy tour in Okinawa. This is the first epidemiological study to estimate the spa health evidence and its effects among health tourism in Japan

Sibship size and prevalence of allergic disorders in Japan: The Ryukyus Child Health Study

Satoko Ohfuji, Yoshihiro Miyake, Masashi Arakawa, Keiko Tanaka, Satoshi Sasaki

PEDIATRIC ALLERGY AND IMMUNOLOGY ( WILEY-BLACKWELL PUBLISHING, INC ) 20 ( 4 ) 377 - 384 2009年06月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

A number of epidemiological studies have reported an inverse association between increasing sibship size and allergic disorders. The present cross-sectional study assessed the association between the number of siblings and the prevalence of allergic disorders during the past 12 months in Japanese schoolchildren. Study subjects were 22,750 children aged 6-15 yr in Okinawa. The outcomes were based on diagnostic criteria from the International Study of Asthma and Allergies in Childhood. Adjustment was made for age, gender, maternal age at childbirth, duration of breastfeeding, region of residence, smoking in the household, paternal and maternal history of asthma, atopic eczema, and allergic rhinitis, and paternal and maternal educational level. Significant exposure-response associations were observed between increasing total sibship size and all outcomes under investigation. Having two or more older siblings was significantly inversely related to the prevalence of atopic eczema and allergic rhinoconjunctivitis, but not wheeze or asthma. Having two or more younger siblings was independently associated with a decreased prevalence of atopic eczema, but not wheeze, asthma, or allergic rhinoconjunctivitis. The inverse relationships between sibship size and the prevalence of allergic disorders under study were weakened with advancing age, although the interactions between age groups were not statistically significant. No significant interactions were found in the association of having three or more siblings with allergic disorders between children with a positive or negative parental allergic history. These results are likely to support the in utero programming hypothesis because it is probable that the in utero environment would change with parity, although our observations could not refute the hygiene hypothesis.

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沖縄観光の展望―健康保養型観光を目指した我々の取り組み事例から―

平良一彦, 荒川雅志

観光科学 ( その他の出版社 ) 1 137 - 149 2009年03月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

海水フローティングの心身のリラクセーション効果に関する無作為割付比較試験

本村純, 荒川雅志, 豊里竹彦, 與古田孝夫

心身医学 ( 一般社団法人日本心身医学会 ) 49 ( 10 ) 1101 - 1109 2009年 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

海洋療法は主に海水の浮力抵抗,粘性や成分特性,海にまつわる素材を生かした施術により治療効果やリラクセーションを図る代替療法であるが,その科学的根拠は十分ではない.本研究では,海水を用いたリラクセーションプログラムの1つであるフローティングの効果について,心臓自律神経系活動,精神特異的ストレスマーカー唾液中クロモグラニンA(CgA),心理的評価STAIを用い無作為割付クロスオーバー比較試験を採用して検討した.その結果,海水フローティング群のみにセッション終了後CgAは有意に減少し,STAIによる状態不安得点では両群ともに有意な減少が認められ,介入後の群間比較では海水フローティング群により大きな減少が認められた.一方,得られたリラクセーション効果が海水特性によるものかは本研究では明らかにされず,今後さらなる検討が必要と考えられた.

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Fatty acid intake and asthma symptoms in Japanese children: The Ryukyus Child Health Study

Y. Miyake, S. Sasaki, M. Arakawa, K. Tanaka, K. Murakami, Y. Ohya

CLINICAL AND EXPERIMENTAL ALLERGY ( WILEY-BLACKWELL ) 38 ( 10 ) 1644 - 1650 2008年10月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Background It has been hypothesized that increased consumption of n-6 polyunsaturated fatty acids and decreased consumption of n-3 polyunsaturated fatty acids have contributed to the recent increased prevalence of asthma. Objectives The present cross-sectional study examined the association of intake of specific types of fatty acids with the prevalence of asthma symptoms using data from the Ryukyus Child Health Study. Methods Study subjects were 25033 schoolchildren aged 6-15 years in Okinawa, Japan. Symptoms of wheeze and asthma were defined according to diagnostic criteria from the International Study of Asthma and Allergies in Childhood. Information on dietary factors was collected using a self-administered brief diet history questionnaire for children. Adjustment was made for age, sex, number of siblings, smoking in the household, body mass index, paternal and maternal history of allergic diseases, and paternal and maternal educational level. Results Intake of polyunsaturated fatty acids, n-3 and n-6 polyunsaturated fatty acids and linoleic acid (18 : 2 n-6) was independently associated with an increased prevalence of wheeze - the multivariate odds ratios for the highest quintile were 1.19 (95% confidence interval [CI], 1.05-1.35), 1.17 (95% CI, 1.03-1.34), 1.19 (95% CI, 1.04-1.35), and 1.20 (95% CI, 1.06-1.37), respectively. There was no measurable relationship of consumption of alpha-linolenic (18 : 3 n-3), eicosapentaenoic (20 : 5 n-3), docosahexaenoic (22 : 6 n-3) or arachidonic acid (20 : 4 n-6) or the ratio of n-3 to n-6 polyunsaturated fatty acids with the prevalence of wheeze. Consumption of total fat, saturated fatty acids, monounsaturated fatty acids and cholesterol were not evidently related to wheeze. No material dose-response association was found between the intake of any of the types of fatty acids considered and the prevalence of asthma. Conclusions The findings suggest that consumption of both n-3 and n-6 polyunsaturated fatty acids, especially linoleic acid, may be associated with an increased prevalence of wheeze.

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Tuberculin reactivity and allergic disorders in schoolchildren, Okinawa, Japan

Y. Miyake, M. Arakawa, K. Tanaka, S. Sasaki, Y. Ohya

CLINICAL AND EXPERIMENTAL ALLERGY ( BLACKWELL PUBLISHING ) 38 ( 3 ) 486 - 492 2008年03月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Background Bacillus Calmette-Guerin (BCG) vaccination triggers a T-helper type 1 response. Whether BCG vaccination and positive tuberculin reactivity are preventive against allergic disorders remains controversial. Objective The current cross-sectional study investigated the relationship of BCG vaccination and tuberculin reactivity with the prevalence of allergic disorders using data from the Ryukyus Child Health Study (RYUCHS). Methods Subjects were 5717 schoolchildren aged 8-11 years in Okinawa, Japan. The RYUCHS collected information on symptoms of allergic disorders and potential confounding factors. The outcomes were based on diagnostic criteria from the International Study of Asthma and Allergies in Childhood. Data on BCG vaccination and tuberculin tests were obtained from school records. Allowance was made for grade, sex, sibship size, smoking in the household, paternal and maternal history of asthma, atopic eczema, and allergic rhinitis, and paternal and maternal educational level. Results No measurable relationship was found between BCG vaccination in infants and the prevalence of allergic disorders. Among 5567 BCG-vaccinated children, positive tuberculin reactivity (induration >= 10 mm) in the first grade was independently associated with a decreased prevalence of wheeze, asthma, and atopic eczema: the multivariate odds ratios for wheeze, asthma, and atopic eczema were 0.80 (95% confidence interval [CI], 0.67-0.94), 0.78 (95% CI, 0.64-0.95), and 0.77 (95% CI, 0.62-0.95), respectively. The inverse associations were more pronounced in children with a negative parental allergic history than in those with a positive parental allergic history. There was no significant relationship between tuberculin reactivity and allergic rhinoconjunctivitis. Conclusions The findings suggest that positive tuberculin reactivity may be inversely associated with the prevalence of wheeze, asthma, and atopic eczema, but not allergic rhinoconjunctivitis, especially among Japanese children without a parental allergic history.

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Correlation between eating habit and the bone mineral density of the children in Yanji City.

Xu Xian-ji, Han Chun-ji, Xu Song-ji, Arakawa M

Chinese Journal of Health Statistics ( その他の出版社 ) 25 ( 1 ) 44 - 45 2008年02月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Dental Caries and Allergic Disorders in Japanese Children: The Ryukyus Child Health Study

Keiko Tanaka, Yoshihiro Miyake, Masashi Arakawa, Satoshi Sasaki, Yukihiro Ohya

JOURNAL OF ASTHMA ( INFORMA HEALTHCARE ) 45 ( 9 ) 795 - 799 2008年 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Background. Dental caries is an infectious disease and is highly prevalent among children. In the etiology of allergic diseases, the hygiene hypothesis contends that infections might confer protection against the development of allergic diseases. The aim of this cross-sectional study was to investigate the association between dental caries and the prevalence of allergic disorders. Methods. Study subjects were 21,792 children 6 to 15 years of age in Okinawa, Japan. Outcomes were based on diagnostic criteria from the International Study of Asthma and Allergies in Childhood. Data on dental caries were obtained from school records. Children were classified as having dental caries if one or more teeth had decayed and/or had been filled. Adjustment was made for sex, age, region of residence, number of siblings, smoking in the household, paternal and maternal history of asthma, atopic eczema, or allergic rhinitis, and paternal and maternal educational level. Results. The prevalence of wheeze, asthma, atopic eczema, and allergic rhinoconjunctivitis in the previous 12 months was 10.8%, 7.6%, 6.8%, and 7.6%, respectively. In an overall analysis, no measurable relationship was found between dental caries and the prevalence of wheeze, asthma, atopic eczema, or allergic rhinoconjunctivitis. However, dental caries was significantly inversely associated with the prevalence of allergic rhinoconjunctivitis only among children with a positive parental allergic history: The adjusted odds ratio was 0.84 (95% confidence interval: 0.72, 0.99). Conclusions. The present findings do not support the hypothesis that dental caries was protective against allergic diseases. However, a parental allergic history may affect the association between dental caries and allergic rhinoconjunctivitis.

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Effects of Floating in Seawater on Stress Reduction.

J MOTOMURA, M ARAKAWA, T YOKOTA

The 39th Conference of the Asia-Pacific Academic Consortium for Public Health, Japan ( その他の出版社 ) 2007年12月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Randomized Controlled Crossover Trial(RCT) of Relaxative Effect in Seawater Floating on Human Physiological Responses.

Arakawa M, Motomura J, Yokota T

The8th International Congress of Physiological Anthropology(ICPA) ( その他の出版社 ) 308 2007年12月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Prevalence of asthma and wheeze in relation to passive smoking in Japanese children

Keiko Tanaka, Yoshihiro Miyake, Masashi Arakawa, Satoshi Sasaki, Yukihiro Ohya

ANNALS OF EPIDEMIOLOGY ( ELSEVIER SCIENCE INC ) 17 ( 12 ) 1004 - 1010 2007年12月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

PURPOSE: Evidence remains inconclusive as to whether environmental tobacco smoke is a risk factor for allergic disorders in childhood. The present large-scale cross-sectional study examined the relationship between passive smoking at home and the prevalence of allergic disorders in Japanese schoolchildren. METHODS: Study subjects were 23,044 children aged 6 to 15 years in Okinawa, Outcomes were based on diagnostic criteria from the International Study of Asthma and Allergies in Childhood. Adjustment was made for sex, age, region of residence, number of siblings, paternal and maternal history of asthma, atopic eczema, or allergic rhinitis, as well as paternal and maternal educational level. RESULTS: The prevalence of wheeze, asthma, atopic eczema, and allergic rhinoconjunctivitis in the previous 12 months was 10.7%, 7.6%, 6.8%, and 7.7%, respectively. Current heavy passive smoking and 7.0 or more pack-years of smoking in the household were independently related to an increased prevalence of wheeze and asthma, especially in children 6 to 10 years of age and children with a positive parental allergic history. There was no dose-response relationship between pack-years of smoking in the household and atopic eczema or allergic rhinoconjunctivitis. CONCLUSIONS: Our findings suggested that environmental tobacco smoke might be associated with an increased prevalence of wheeze and asthma in Japanese children.

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Cross-sectional study of allergic disorders associated with breastfeeding in Japan: The Ryukyus Child Health Study

Yoshihiro Miyake, Masashi Arakawa, Keiko Tanaka, Satoshi Sasaki, Yukihiro Ohya

PEDIATRIC ALLERGY AND IMMUNOLOGY ( BLACKWELL PUBLISHING ) 18 ( 5 ) 433 - 440 2007年08月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

Uncertainties remain as to whether breastfeeding is protective against childhood allergic disorders. Positive relationships of breastfeeding with asthma and atopic eczema were observed in two previous Japanese studies. This cross-sectional study investigated the association between the feeding pattern after birth and the prevalence of allergic disorders during the past 12 months in Japanese schoolchildren. Study subjects were 24,077 children aged 6-15 yr in Okinawa. The outcomes were based on diagnostic criteria from the International Study of Asthma and Allergies in Childhood. Allowance was made for age, sex, number of siblings, smoking in the household, paternal and maternal history of asthma, atopic eczema, and allergic rhinitis, and paternal and maternal educational level. Breastfeeding, regardless of exclusivity, for 13 months or longer and exclusive breastfeeding for 4-11 months were independently associated with a higher prevalence of atopic eczema, particularly among children without a parental allergic history. A clear positive dose-response relationship was observed between prolonged duration of breastfeeding, regardless of exclusivity, but not exclusive breastfeeding, and the prevalence of atopic eczema. We found a significant positive trend for atopic eczema across the three categories (formula milk, partial and exclusive breastfeeding) in the first 4 months of life although the odds ratio for exclusive breastfeeding was not statistically significant. No material association was found between the feeding pattern after birth and the prevalence of wheeze or allergic rhinoconjunctivitis. Prolonged breastfeeding may be associated with a higher prevalence of atopic eczema in Japanese children.

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沖縄における新百歳長寿者の生活及び健康

平良一彦, 荒川雅志

琉球大学アジア太平洋島嶼研究センター報 ( その他の出版社 ) 65 - 113 2007年03月

掲載種別: 研究論文（大学，研究機関紀要）

沖縄型健康保養観光の展望 : 健康科学と観光の融合を目指す当分野の先行的研究事例

平良一彦, 荒川雅志, 笠原大吾, Taira Kazuhiko, Arakawa Masashi, Kasahara Daigo

琉球大学観光科学 = Journal of tourism sciences. University of the Ryukyus ( 琉球大学法文学部 ) ( 1 ) 137 - 149 2007年03月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

When Okinawa tourism is in the process of quantitative and qualitative change, it is now strongly expected to utilize healthy resources of "Longevity Prefecture Okinawa" and establish unique tourism for health and recuperation. Now we are scientifically evaluating subjective and objective effects using keywords such as "natural environment of Okinawa," "Spiritual climate," "healing," "health of mind and body" and "food," and trying to contribute to development of health and recuperation tourism program and business in Okinawa. We use intellectual resources of the University of Ryukyus and develop the tourism program in collaboration with private sectors. We also conduct basic experiments on use of marine resources of Okinawa for spa. Spa and esthetic technology and branding will greatly influence the future stay-type tourism. One of our goals is to increase the level of the spa and esthetic technology and branding. We are making our efforts to achieve the goal and constantly getting results. This paper will show some of our achievements.

地域在宅高齢者における日常生活体力の実態

平良一彦, 荒川雅志, 笠原大吾, 嘉手苅初子, 新城澄枝, 東盛キヨ子, 大塚千絵, 渡部善喜, Taira Kazuhiko, Arakawa Masashi, Kasahara Daigo, Kadekaru Hatuko, Shinjo Sumie, Higashimori Kiyoko, Otuka Chie, Watanabe Zenki

琉球大学教育学部紀要 ( 琉球大学教育学部 ) 67 231 - 241 2005年09月 [ 査読有り ]

掲載種別: 研究論文（学術雑誌）

To examine levels of functional fitness of elderly people living at home, a cross-sectional survey was conducted targeting 385 persons, who were 65 years old and over.The functional fitness for daily life was measured by the following 4 tests: standing test, walking test, hand performance test and self-care performance test. Results of standing and walking tests showed that males stand up and walk significantly faster than females. With advancing age their performance for all 4 tests got slower, and there was statistically significant difference between the young-old age group and the old-old age group.The results suggest that the aging strongly affects levels of functional fitness of elderly people living at home.

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