Published Papers - Masuzaki Hiroaki

Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele.

Davy PMC, Willcox DC, Shimabukuro M, Donlon TA, Torigoe T, Suzuki M, Higa M, Masuzaki H, Sata M, Chen R, Murkofsky RL, Morris BJ, Lim E, Allsopp RC, Willcox BJ

The journals of gerontology. Series A, Biological sciences and medical sciences ( Journals of Gerontology - Series A Biological Sciences and Medical Sciences )  73 ( 11 ) 1448 - 1452   2018.10 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Minimal shortening of leukocyte telomere length across age groups in a cross-sectional study for carriers of a longevity-associated FOXO3 allele

Davy PMC, Willcox DC, Shimabukuro M, Donlon TA, Torigoe T, Suzuki M, Higa M, Masuzaki H, Sata M, Chen R, Murkofsky R, Morris BJ, Lim E, Allsopp RC, Willcox BJ

J Gerontol A Biol Sci Med Sci   73 ( 11 ) 1448 - 1452   2018.10 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

Usefulness of epicardial adipose tissue volume to predict recurrent atrial fibrillation after radiofrequency catheter ablation

Maeda M, Oba K, Yamaguchi S, Arasaki O, Sata M, Masuzaki H, Shimabukuro M

Am J Cardiol   122 ( 10 ) 1694 - 1700   2018.10 [ Peer Review Accepted ]

Type of publication: Research paper (other science council materials etc.)

Embryonic development of GABAergic terminals in the mouse hypothalamic nuclei involved in feeding behavior

Kobayashi M, Shimizu-Okabe C, Kim J, Kobayashi S, Matsushita M, Masuzaki H, Takayama C

Neurosci Res   134   39 - 48   2018.09 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

Embryonic development of GABAergic terminals in the mouse hypothalamic nuclei involved in feeding behavior.

Kobayashi M, Shimizu-Okabe C, Kim J, Kobayashi S, Matsushita M, Masuzaki H, Takayama C

Neuroscience research ( Neuroscience Research )  134   39 - 48   2018.09 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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高悪性度成人T細胞白血病/リンパ腫の予後予測におけるFDG-PET/CTの有用性(Clinical usefulness of FDG-PET/CT for predicting prognosis of aggressive ATL)

仲地 佐和子, 森島 聡子, 岡田 真広, 東江 ゆりか, 内堀 幸恵, 北村 紗希子, 友利 昌平, 花城 多恵子, 島袋 奈津紀, 玉城 啓太, 手登根 伊織, 森近 一穂, 西 由希子, 加留部 謙之輔, 福島 卓也, 益崎 裕章

臨床血液 ( (一社)日本血液学会-東京事務局 )  59 ( 9 ) 1597 - 1597   2018.09

Type of publication: Research paper (other science council materials etc.)

Protective Role of Myelocytic Nitric Oxide Synthases against Hypoxic Pulmonary Hypertension in Mice.

Ogoshi T, Tsutsui M, Kido T, Sakanashi M, Naito K, Oda K, Ishimoto H, Yamada S, Wang KY, Toyohira Y, Izumi H, Masuzaki H, Shimokawa H, Yanagihara N, Yatera K, Mukae H

American journal of respiratory and critical care medicine ( American Journal of Respiratory and Critical Care Medicine )  198 ( 2 ) 232 - 244   2018.07 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Evaluation of two prognostic indices for adult T cell leukemia/lymphoma in the subtropical endemic area, Okinawa, Japan

Tamaki K, Morishima S, Nomura S, Nishi Y, Nakachi S, Kitamura S, Uchibori S, Tomori S, Hanashiro T, Shimabukuro N, Tedokon I, Morichika K, Taira N, Tomoyose T, Takashi Miyagi T, Karimata K, Ohama M, Yamanoha A, Tamaki K, Hayashi M, Uchihara J, Ohshiro K, Asakura Y, Kuba-Miyara M, Karube K, Fukushima T, Masuzaki H

Cancer Sci   109 ( 7 ) 2286 - 2293   2018.07 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

Protective Role of Myelocytic Nitric Oxide Synthases Against Hypoxic Pulmonary Hypertension in Mice

Ogoshi T, Tsutsui M, Kido T, Sakanashi M, Naito K, Oda K, Ishimoto H, Yamada S, Wang KY, Toyohira Y, Izumi H, Masuzaki H, Shimokawa H, Yanagihara N, Yatera K, Mukae H

Am J Respir Crit Care Med   198 ( 2 ) 232 - 244   2018.07 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

Evaluation of two prognostic indices for adult T-cell leukemia/lymphoma in the subtropical endemic area, Okinawa, Japan.

Tamaki K, Morishima S, Nomura S, Nishi Y, Nakachi S, Kitamura S, Uchibori S, Tomori S, Hanashiro T, Shimabukuro N, Tedokon I, Morichika K, Taira N, Tomoyose T, Miyagi T, Karimata K, Ohama M, Yamanoha A, Tamaki K, Hayashi M, Uchihara JN, Ohshiro K, Asakura Y, Kuba-Miyara M, Karube K, Fukushima T, Masuzaki H

Cancer science ( Cancer Science )  109 ( 7 ) 2286 - 2293   2018.07 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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The efficacy of adjunct tacrolimus treatment in pregnancy outcomes in patients with systemic lupus erythematosus.

Ichinose K, Sato S, Kitajima Y, Horai Y, Fujikawa K, Umeda M, Fukui S, Nishino A, Koga T, Kawashiri SY, Iwamoto N, Tamai M, Nakamura H, Origuchi T, Yasuhi I, Masuzaki H, Kawakami A

Lupus   27 ( 8 ) 1312 - 1320   2018.07 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Effect of the Epicardial Adipose Tissue Volume on the Prevalence of Paroxysmal and Persistent Atrial Fibrillation.

Oba K, Maeda M, Maimaituxun G, Yamaguchi S, Arasaki O, Fukuda D, Yagi S, Hirata Y, Nishio S, Iwase T, Takao S, Kusunose K, Yamada H, Soeki T, Wakatsuki T, Harada M, Masuzaki H, Sata M, Shimabukuro M

Circulation journal : official journal of the Japanese Circulation Society ( 一般社団法人 日本循環器学会 )  82 ( 7 ) 1778 - 1787   2018.06 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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<p><b><i>Background:</i></b>Although increasing evidence suggests that epicardial adipose tissue volume (EATV) is associated with atrial fibrillation (AF), it is controversial whether there is a dose-response relationship of increasing EATV along the continuum of AF. We evaluated the effect of the EATV on the prevalence of paroxysmal AF (PAF) and persistent AF (PeAF) and the relationships with cardiac structure and functional remodeling.</p><p><b><i>Methods and Results:</i></b>Subjects who underwent multidetector computed tomography (MDCT) coronary angiography because of symptoms suggestive of coronary artery disease were divided into sinus rhythm (SR) (n=112), PAF (n=133), and PeAF (n=71) groups. The EATV index (EATV/body surface area, mL/m²) was strongly associated with the prevalence of PAF and PeAF on the model adjusted for known AF risk factors. The effect of the EATV index on the prevalence of PeAF, but not on that of PAF, was modified by the left atrial (LA) dimension, suggesting that extension of the LA dimension is related to EATV expansion in PeAF. The cutoff value of the EATV index for the prevalence was higher in PeAF than in PAF (64 vs. 55 mL/m², P<0.01).</p><p><b><i>Conclusions:</i></b>The EATV index is associated with the prevalence of PAF and PeAF, and its cutoff values are predictive for PAF and PeAF development independently of other AF risk factors.</p>

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Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy.

Suzumori N, Sekizawa A, Ebara T, Samura O, Sasaki A, Akaishi R, Wada S, Hamanoue H, Hirahara F, Izumi H, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Yamashita T, Okai T, Kamei Y, Namba A, Murotsuki J, Tanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Nagamatsu T, Watanabe A, Shirato N, Yotsumoto J, Nishiyama M, Hirose T, Sago H

European journal of obstetrics, gynecology, and reproductive biology   224   165 - 169   2018.05 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Two consecutive successful live birth in woman with 17α hydroxylase deficiency by frozen-thaw embryo transfer under hormone replacement endometrium preparation.

Kitajima M, Miura K, Inoue T, Murakami Y, Kitajima Y, Murakami N, Taniguchi K, Yoshiura KI, Masuzaki H

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology   34 ( 5 ) 381 - 384   2018.05 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Reference values for circulating pregnancy-associated microRNAs in maternal plasma and their clinical usefulness in uncomplicated pregnancy and hypertensive disorder of pregnancy.

Murakami Y, Miura K, Sato S, Higashijima A, Hasegawa Y, Miura S, Yoshiura KI, Masuzaki H

The journal of obstetrics and gynaecology research   44 ( 5 ) 840 - 851   2018.05 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Natural Course of Human T-Cell Leukemia Virus Type 1 Proviral DNA Levels in Carriers During Pregnancy.

Fuchi N, Miura K, Tsukiyama T, Sasaki D, Ishihara K, Tsuruda K, Hasegawa H, Miura S, Yanagihara K, Masuzaki H

The Journal of infectious diseases   217 ( 9 ) 1383 - 1389   2018.04 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Relevant obstetric factors associated with fetal heart rate monitoring for cerebral palsy in pregnant women with hypertensive disorder of pregnancy.

Hasegawa J, Ikeda T, Toyokawa S, Jojima E, Satoh S, Ichizuka K, Tamiya N, Nakai A, Fujimori K, Maeda T, Masuzaki H, Takeda S, Suzuki H, Ueda S, Ikenoue T, Prevention Recurrence Committee, Japan Obstetric Compensation System for Cerebral Palsy

The journal of obstetrics and gynaecology research   44 ( 4 ) 647 - 654   2018.04 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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マウスにおいて亜麻仁油とエクストラヴァージンオリーブオイルの食餌摂取は消化管細菌叢を調節して肥満と代謝機能障害を予防する(Dietary flaxseed and extra virgin olive oils modulate gut microbiota, protecting against obesity and metabolic dysfunction in mice)

ミルマン・ジャスミン, 岡本 士毅, 上間 次己, 與那嶺 正人, 難波 豊隆, 益崎 裕章

日本内分泌学会雑誌 ( (一社)日本内分泌学会 )  94 ( 1 ) 316 - 316   2018.04

Type of publication: Research paper (other science council materials etc.)

亜麻仁油とextra virgin olive oilは腸内細菌叢、腸バリア、免疫機能に影響を及ぼし健全な代謝を維持する(Flaxseed and extra virgin olive oils impact gut microbiota, gut barrier and immune function, supporting metabolic health)

Millman Frances Jasmine, 岡本 士毅, 上間 次己, 與那嶺 正人, 難波 豊隆, 益崎 裕章

糖尿病 ( (一社)日本糖尿病学会 )  61 ( Suppl.1 ) S - 266   2018.04

Type of publication: Research paper (other science council materials etc.)

Activation of AMPK-Regulated CRH Neurons in the PVH is Sufficient and Necessary to Induce Dietary Preference for Carbohydrate over Fat.

Okamoto S, Sato T, Tateyama M, Kageyama H, Maejima Y, Nakata M, Hirako S, Matsuo T, Kyaw S, Shiuchi T, Toda C, Sedbazar U, Saito K, Asgar NF, Zhang B, Yokota S, Kobayashi K, Foufelle F, Ferré P, Nakazato M, Masuzaki H, Shioda S, Yada T, Kahn BB, Minokoshi Y

Cell reports ( Cell Reports )  22 ( 3 ) 706 - 721   2018.01 [ Peer Review Accepted ]

Type of publication: Research paper (scientific journal)

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Food selection is essential for metabolic homeostasis and is influenced by nutritional state, food palatability, and social factors such as stress. However, the mechanism responsible for selection between a high-carbohydrate diet (HCD) and a high-fat diet (HFD) remains unknown. Here, we show that activation of a subset of corticotropin-releasing hormone (CRH)-positive neurons in the rostral region of the paraventricular hypothalamus (PVH) induces selection of an HCD over an HFD in mice during refeeding after fasting, resulting in a rapid recovery from the change in ketone metabolism. These neurons manifest activation of AMP-activated protein kinase (AMPK) during food deprivation, and this activation is necessary and sufficient for selection of an HCD over an HFD. Furthermore, this effect is mediated by carnitine palmitoyltransferase 1c (CPT1c). Thus, our results identify the specific neurons and intracellular signaling pathway responsible for regulation of the complex behavior of selection between an HCD and an HFD. VIDEO ABSTRACT.

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